Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 20 studies | 48% ± 18% | |
| retinal rod cell | 8 studies | 63% ± 33% | |
| retinal cone cell | 6 studies | 64% ± 26% | |
| vein endothelial cell | 6 studies | 55% ± 28% | |
| capillary endothelial cell | 4 studies | 33% ± 13% | |
| endothelial cell of artery | 4 studies | 45% ± 20% | |
| microglial cell | 3 studies | 61% ± 6% | |
| endothelial cell of lymphatic vessel | 3 studies | 29% ± 7% | |
| endothelial cell of vascular tree | 3 studies | 63% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| eye | 6 studies | 40% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 740.87 | 459 / 459 | 42% | 2.07 | 472 / 1118 |
| ovary | 78% | 163.48 | 140 / 180 | 53% | 2.00 | 226 / 430 |
| thymus | 99% | 313.60 | 646 / 653 | 18% | 0.27 | 107 / 605 |
| prostate | 98% | 301.79 | 240 / 245 | 17% | 0.26 | 85 / 502 |
| uterus | 100% | 466.08 | 170 / 170 | 15% | 0.32 | 67 / 459 |
| lung | 100% | 769.74 | 578 / 578 | 10% | 0.21 | 118 / 1155 |
| esophagus | 97% | 250.09 | 1399 / 1445 | 11% | 0.18 | 21 / 183 |
| bladder | 100% | 273.76 | 21 / 21 | 8% | 0.16 | 40 / 504 |
| kidney | 65% | 93.55 | 58 / 89 | 43% | 1.06 | 384 / 901 |
| brain | 85% | 164.19 | 2235 / 2642 | 20% | 0.32 | 142 / 705 |
| adipose | 100% | 814.70 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| heart | 100% | 424.22 | 859 / 861 | 0% | 0 | 0 / 0 |
| spleen | 97% | 356.59 | 234 / 241 | 0% | 0 | 0 / 0 |
| stomach | 91% | 175.35 | 327 / 359 | 6% | 0.09 | 17 / 286 |
| intestine | 92% | 213.30 | 890 / 966 | 4% | 0.05 | 21 / 527 |
| muscle | 83% | 118.62 | 668 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 82% | 184.39 | 1089 / 1335 | 0% | 0 | 0 / 0 |
| skin | 54% | 81.48 | 971 / 1809 | 8% | 0.53 | 40 / 472 |
| pancreas | 27% | 31.45 | 89 / 328 | 9% | 0.14 | 16 / 178 |
| adrenal gland | 10% | 20.13 | 27 / 258 | 12% | 0.22 | 28 / 230 |
| eye | 0% | 0 | 0 / 0 | 13% | 1.71 | 10 / 80 |
| liver | 3% | 2.35 | 6 / 226 | 9% | 0.33 | 36 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.12 | 3 / 45 |
| peripheral blood | 0% | 0.54 | 4 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0034220 | Biological process | monoatomic ion transmembrane transport |
| GO_1902476 | Biological process | chloride transmembrane transport |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0034707 | Cellular component | chloride channel complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0046983 | Molecular function | protein dimerization activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0005229 | Molecular function | intracellularly calcium-gated chloride channel activity |
| Gene name | ANO2 |
| Protein name | Anoctamin-2 Anoctamin Anoctamin-2 (Transmembrane protein 16B) |
| Synonyms | TMEM16B C12orf3 |
| Description | FUNCTION: Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina. . |
| Accessions | Q9NQ90 A0A804HIY3 ENST00000682330.1 ENST00000650848.1 [Q9NQ90-1] F5H806 ENST00000545860.1 ENST00000356134.9 [Q9NQ90-2] ENST00000327087.12 [Q9NQ90-2] F1T0L7 |
