ALX4 | OmnibusX

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ALX4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	98%	602.34	451 / 459	35%	1.75	391 / 1118
uterus	89%	153.39	151 / 170	17%	1.97	77 / 459
skin	92%	208.61	1669 / 1809	11%	1.15	53 / 472
adipose	88%	78.36	1057 / 1204	0%	0	0 / 0
muscle	72%	54.57	578 / 803	0%	0	0 / 0
thymus	70%	36.25	460 / 653	1%	0.05	8 / 605
brain	55%	32.19	1462 / 2642	15%	0.98	106 / 705
esophagus	35%	14.61	502 / 1445	17%	1.61	31 / 183
prostate	24%	39.83	60 / 245	26%	0.82	132 / 502
bladder	38%	10.57	8 / 21	3%	0.15	16 / 504
blood vessel	33%	14.78	439 / 1335	0%	0	0 / 0
adrenal gland	7%	14.29	18 / 258	21%	2.75	48 / 230
kidney	24%	15.61	21 / 89	3%	0.15	27 / 901
heart	25%	7.78	218 / 861	0%	0	0 / 0
ovary	12%	4.34	22 / 180	11%	0.61	46 / 430
lung	8%	3.86	48 / 578	6%	0.28	68 / 1155
stomach	11%	2.71	38 / 359	3%	0.06	8 / 286
pancreas	11%	3.08	37 / 328	1%	0.02	1 / 178
tonsil	0%	0	0 / 0	9%	0.41	4 / 45
eye	0%	0	0 / 0	5%	0.11	4 / 80
intestine	3%	0.50	25 / 966	1%	0.03	5 / 527
spleen	2%	0.53	6 / 241	0%	0	0 / 0
liver	0%	0	0 / 226	1%	0.13	3 / 406
peripheral blood	0%	0.03	2 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0009791	Biological process	post-embryonic development
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0048704	Biological process	embryonic skeletal system morphogenesis
GO_0042733	Biological process	embryonic digit morphogenesis
GO_0035115	Biological process	embryonic forelimb morphogenesis
GO_0035116	Biological process	embryonic hindlimb morphogenesis
GO_0060021	Biological process	roof of mouth development
GO_0042981	Biological process	regulation of apoptotic process
GO_0007517	Biological process	muscle organ development
GO_0001942	Biological process	hair follicle development
GO_0048565	Biological process	digestive tract development
GO_0009952	Biological process	anterior/posterior pattern specification
GO_0001501	Biological process	skeletal system development
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005654	Cellular component	nucleoplasm
GO_0000785	Cellular component	chromatin
GO_0005667	Cellular component	transcription regulator complex
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0001228	Molecular function	DNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000977	Molecular function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0005515	Molecular function	protein binding
GO_0071837	Molecular function	HMG box domain binding

Gene name	ALX4
Protein name	Homeobox protein aristaless-like 4
Synonyms	KIAA1788
Description	FUNCTION: Transcription factor involved in skull and limb development. Plays an essential role in craniofacial development, skin and hair follicle development. .
Accessions	Q9H161 ENST00000652299.1

ALX4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review