AHRR | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of AHRR at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
spleen	100%	1569.02	241 / 241	0%	0	0 / 0
skin	100%	1516.11	1805 / 1809	0%	0.00	1 / 472
ovary	89%	709.60	160 / 180	0%	0	0 / 430
intestine	80%	469.36	772 / 966	0%	0.01	2 / 527
thymus	76%	384.62	496 / 653	0%	0	0 / 605
lung	73%	589.63	422 / 578	1%	0.01	8 / 1155
uterus	68%	417.38	115 / 170	0%	0	0 / 459
bladder	67%	930.19	14 / 21	0%	0.01	1 / 504
esophagus	65%	310.26	946 / 1445	0%	0	0 / 183
prostate	61%	239.50	150 / 245	0%	0	0 / 502
breast	56%	191.93	259 / 459	0%	0.00	1 / 1118
stomach	55%	202.59	198 / 359	0%	0.01	1 / 286
adipose	54%	235.63	647 / 1204	0%	0	0 / 0
kidney	51%	162.25	45 / 89	0%	0.00	1 / 901
brain	50%	185.85	1327 / 2642	0%	0	0 / 705
adrenal gland	37%	137.11	95 / 258	0%	0.01	1 / 230
blood vessel	29%	83.29	381 / 1335	0%	0	0 / 0
peripheral blood	24%	1494.07	221 / 929	0%	0	0 / 0
pancreas	22%	42.14	72 / 328	0%	0	0 / 178
heart	17%	51.14	149 / 861	0%	0	0 / 0
liver	8%	28.40	19 / 226	0%	0	0 / 406
muscle	7%	65.21	54 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0030522	Biological process	intracellular receptor signaling pathway
GO_0006805	Biological process	xenobiotic metabolic process
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0034751	Cellular component	aryl hydrocarbon receptor complex
GO_0005654	Cellular component	nucleoplasm
GO_0000785	Cellular component	chromatin
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0004879	Molecular function	nuclear receptor activity
GO_0046983	Molecular function	protein dimerization activity
GO_0005515	Molecular function	protein binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0000976	Molecular function	transcription cis-regulatory region binding

Gene name	AHRR
Protein name	Aryl hydrocarbon receptor repressor (HCG1985585, isoform CRA_a) Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor repressor (AhR repressor) (AhRR) (Class E basic helix-loop-helix protein 77) (bHLHe77)
Synonyms	BHLHE77 hCG_1985585 KIAA1234
Description	FUNCTION: Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site. .
Accessions	E5RHE0 ENST00000652417.2 A0A494BZY4 ENST00000515206.6 A9YTQ3 ENST00000511487.1 H0YA43 ENST00000506456.1 ENST00000504625.1 ENST00000514523.1 ENST00000684583.1 E5RGQ2 ENST00000316418.10 D6RE68 G3V143 E5RFG4 A0A7I2PK40 ENST00000510400.5

AHRR report