Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 12 studies | 27% ± 10% | |
| glutamatergic neuron | 10 studies | 46% ± 24% | |
| fibroblast | 10 studies | 22% ± 5% | |
| astrocyte | 10 studies | 27% ± 11% | |
| oligodendrocyte precursor cell | 7 studies | 28% ± 10% | |
| interneuron | 6 studies | 35% ± 14% | |
| GABAergic neuron | 6 studies | 47% ± 19% | |
| smooth muscle cell | 6 studies | 26% ± 6% | |
| cardiac muscle cell | 5 studies | 30% ± 8% | |
| ciliated cell | 5 studies | 33% ± 15% | |
| pericyte | 5 studies | 25% ± 7% | |
| type I pneumocyte | 5 studies | 47% ± 8% | |
| type II pneumocyte | 5 studies | 37% ± 6% | |
| neuron | 4 studies | 26% ± 8% | |
| granule cell | 4 studies | 33% ± 17% | |
| macrophage | 4 studies | 20% ± 5% | |
| epithelial cell | 4 studies | 34% ± 22% | |
| GABAergic interneuron | 3 studies | 27% ± 9% | |
| retinal pigment epithelial cell | 3 studies | 35% ± 14% | |
| club cell | 3 studies | 31% ± 5% | |
| lymphocyte | 3 studies | 20% ± 2% | |
| basal cell | 3 studies | 28% ± 9% | |
| endothelial cell of lymphatic vessel | 3 studies | 18% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 100% | 2261.59 | 1806 / 1809 | 99% | 16.59 | 467 / 472 |
| kidney | 100% | 2107.55 | 89 / 89 | 98% | 19.56 | 886 / 901 |
| esophagus | 99% | 3122.97 | 1433 / 1445 | 99% | 13.80 | 181 / 183 |
| pancreas | 100% | 2498.92 | 327 / 328 | 98% | 9.94 | 175 / 178 |
| thymus | 100% | 6583.32 | 653 / 653 | 98% | 27.56 | 592 / 605 |
| liver | 100% | 2387.11 | 226 / 226 | 98% | 12.94 | 397 / 406 |
| breast | 100% | 2405.13 | 457 / 459 | 96% | 18.87 | 1078 / 1118 |
| lung | 100% | 4294.62 | 578 / 578 | 96% | 12.39 | 1106 / 1155 |
| intestine | 100% | 2926.88 | 966 / 966 | 94% | 8.43 | 494 / 527 |
| adrenal gland | 100% | 2021.64 | 258 / 258 | 91% | 8.94 | 210 / 230 |
| uterus | 100% | 3113.18 | 170 / 170 | 91% | 9.35 | 417 / 459 |
| brain | 91% | 1831.37 | 2406 / 2642 | 97% | 9.68 | 686 / 705 |
| stomach | 89% | 2008.98 | 321 / 359 | 97% | 11.49 | 276 / 286 |
| prostate | 98% | 1746.20 | 239 / 245 | 82% | 5.20 | 410 / 502 |
| ovary | 100% | 3248.68 | 180 / 180 | 77% | 5.75 | 331 / 430 |
| bladder | 100% | 3633.62 | 21 / 21 | 74% | 5.85 | 372 / 504 |
| blood vessel | 100% | 6118.45 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 19.94 | 80 / 80 |
| muscle | 100% | 10544.01 | 803 / 803 | 0% | 0 | 0 / 0 |
| adipose | 100% | 2350.61 | 1200 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 98% | 1318.22 | 237 / 241 | 0% | 0 | 0 / 0 |
| heart | 96% | 3020.22 | 830 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 10.93 | 41 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 24% | 0.97 | 7 / 29 |
| peripheral blood | 10% | 98.30 | 97 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_0035556 | Biological process | intracellular signal transduction |
| GO_0006171 | Biological process | cAMP biosynthetic process |
| GO_0071880 | Biological process | adenylate cyclase-activating adrenergic receptor signaling pathway |
| GO_0001701 | Biological process | in utero embryonic development |
| GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| GO_0030424 | Cellular component | axon |
| GO_0005829 | Cellular component | cytosol |
| GO_0016020 | Cellular component | membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030425 | Cellular component | dendrite |
| GO_0004016 | Molecular function | adenylate cyclase activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | ADCY9 |
| Protein name | adenylate cyclase (EC 4.6.1.1) Alternative protein ADCY9 Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (ACIX) (Adenylyl cyclase 9) (AC9) Adenylate cyclase 9 |
| Synonyms | KIAA0520 |
| Description | FUNCTION: Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein-coupled receptors . Contributes to signaling cascades activated by CRH (corticotropin-releasing factor), corticosteroids and beta-adrenergic receptors . . |
| Accessions | I3L342 ENST00000571467.1 I3NI20 ENST00000576936.5 I3L300 L0R6C2 O60503 ENST00000294016.8 ENST00000572288.1 |