ADAMTS3 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADAMTS3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	97%	200.87	237 / 245	75%	2.25	375 / 502
thymus	100%	385.06	652 / 653	63%	1.64	384 / 605
kidney	92%	208.42	82 / 89	71%	2.60	638 / 901
adrenal gland	100%	280.63	257 / 258	53%	1.70	121 / 230
ovary	100%	670.46	180 / 180	49%	1.44	211 / 430
breast	99%	1118.25	455 / 459	40%	1.09	451 / 1118
lung	100%	374.69	576 / 578	39%	1.31	453 / 1155
uterus	98%	565.18	166 / 170	27%	1.27	126 / 459
skin	75%	117.60	1355 / 1809	42%	2.49	196 / 472
bladder	95%	204.24	20 / 21	13%	0.29	65 / 504
adipose	100%	568.97	1202 / 1204	0%	0	0 / 0
brain	59%	201.60	1553 / 2642	41%	2.25	287 / 705
blood vessel	99%	350.34	1328 / 1335	0%	0	0 / 0
esophagus	69%	137.11	998 / 1445	27%	0.78	49 / 183
spleen	81%	116.22	195 / 241	0%	0	0 / 0
intestine	71%	100.22	684 / 966	9%	0.18	47 / 527
stomach	51%	143.12	182 / 359	13%	0.27	36 / 286
heart	58%	125.79	503 / 861	0%	0	0 / 0
pancreas	21%	19.12	69 / 328	31%	0.61	56 / 178
liver	23%	33.97	53 / 226	8%	0.18	34 / 406
muscle	24%	27.46	191 / 803	0%	0	0 / 0
peripheral blood	22%	54.11	209 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	18%	0.35	8 / 45
lymph node	0%	0	0 / 0	17%	0.23	5 / 29
eye	0%	0	0 / 0	5%	0.07	4 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0010573	Biological process	vascular endothelial growth factor production
GO_0001701	Biological process	in utero embryonic development
GO_0030198	Biological process	extracellular matrix organization
GO_0016485	Biological process	protein processing
GO_1900748	Biological process	positive regulation of vascular endothelial growth factor signaling pathway
GO_0030574	Biological process	collagen catabolic process
GO_0097435	Biological process	supramolecular fiber organization
GO_0006508	Biological process	proteolysis
GO_0030199	Biological process	collagen fibril organization
GO_0032964	Biological process	collagen biosynthetic process
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0070062	Cellular component	extracellular exosome
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0031012	Cellular component	extracellular matrix
GO_0008201	Molecular function	heparin binding
GO_0004175	Molecular function	endopeptidase activity
GO_0008270	Molecular function	zinc ion binding
GO_0004222	Molecular function	metalloendopeptidase activity
GO_0005515	Molecular function	protein binding

Gene name	ADAMTS3
Protein name	A disintegrin and metalloproteinase with thrombospondin motifs 3 (ADAM-TS 3) (ADAM-TS3) (ADAMTS-3) (EC 3.4.24.-) (Procollagen II N-proteinase) (PC II-NP) (Procollagen II amino propeptide-processing enzyme) ADAMTS3 protein
Synonyms	KIAA0366
Description	FUNCTION: Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens.
Accessions	Q96AY5 ENST00000286657.10 O15072

ADAMTS3 report