ABI3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_2000774Biological processpositive regulation of cellular senescence
GO_0001764Biological processneuron migration
GO_0010593Biological processnegative regulation of lamellipodium assembly
GO_0030036Biological processactin cytoskeleton organization
GO_0018108Biological processpeptidyl-tyrosine phosphorylation
GO_0061001Biological processregulation of dendritic spine morphogenesis
GO_0030334Biological processregulation of cell migration
GO_0002357Biological processdefense response to tumor cell
GO_1900028Biological processnegative regulation of ruffle assembly
GO_0099151Biological processregulation of postsynaptic density assembly
GO_1903077Biological processnegative regulation of protein localization to plasma membrane
GO_0098858Cellular componentactin-based cell projection
GO_0043197Cellular componentdendritic spine
GO_0016020Cellular componentmembrane
GO_0043198Cellular componentdendritic shaft
GO_0014069Cellular componentpostsynaptic density
GO_0005737Cellular componentcytoplasm
GO_0030027Cellular componentlamellipodium
GO_0031209Cellular componentSCAR complex
GO_0051015Molecular functionactin filament binding
GO_0042802Molecular functionidentical protein binding
GO_0035591Molecular functionsignaling adaptor activity
GO_0017124Molecular functionSH3 domain binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameABI3
Protein nameABI family member 3
Alternative protein ABI3
ABI gene family member 3 (New molecule including SH3) (Nesh)
SynonymsNESH
DescriptionFUNCTION: May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility. .

AccessionsENST00000573347.5
ENST00000225941.6 [Q9P2A4-1]
L8ECG8
I3L3W4
I3L1X2
ENST00000571035.1
ENST00000419580.6 [Q9P2A4-2]
Q9P2A4