Name | histone H3K27 trimethyltransferase activity |
ID | GO_0140951 |
collection_id | Molecular function |
Exact synonym | histone H3-K27 trimethylase activity, histone H3K27 mono/di/trimethylase activity, histone H3K27 trimethylase activity, histone lysine N-trimethyltransferase activity (H3-K27 specific) |
Description | Catalysis of the reaction: L-lysyl27-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl27-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me3. |
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