very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity

I. Literature review

[source]
Namevery-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity
IDGO_0102158
collection_id

Molecular function

Exact synonym

very-long-chain 3-hydroxyacyl-CoA dehydratase activity

Description

Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA = H2O + a very-long-chain (2E)-enoyl-CoA. This reaction is the third (dehydration) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit.

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Genes
HACD2HACD1HACD4HACD3