elongin complex

I. Literature review

[source]
Nameelongin complex
IDGO_0070449
collection_id

Cellular component

Exact synonym

elongin (SIII) complex, transcription elongation factor SIII complex, transcription factor B (SIII) complex

Description

A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits.

Comment

See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'.

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Genes