ELOA report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ELOA at tissue level.

III. Associated gene sets

GO_0006368Biological processtranscription elongation by RNA polymerase II
GO_0006367Biological processtranscription initiation at RNA polymerase II promoter
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005615Cellular componentextracellular space
GO_0090734Cellular componentsite of DNA damage
GO_0070449Cellular componentelongin complex
GO_0005654Cellular componentnucleoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameELOA
Protein nameElongin-A (EloA) (Elongin 110 kDa subunit) (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Transcription elongation factor B polypeptide 3)
SynonymsMSTP059
TCEB3
DescriptionFUNCTION: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). .; FUNCTION: As part of a multisubunit complex composed of elongin BC complex (ELOB and ELOC), elongin A/ELOA, RBX1 and CUL5; polyubiquitinates monoubiquitinated POLR2A. .

AccessionsENST00000613537.5 [Q14241-2]
Q14241