parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 1
OPTNHDAC6MFN2
neuronepithelial cell
5 studies
Group 2
PRKN
neuronmyeloid cellconnective tissue cellglial cellendothelial cellepithelial cell
60 studies

II. Literature review

[source]
Nameparkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
IDGO_0061734
collection_id

Biological process

Exact synonym

PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization, Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization

Description

A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule.

External URL
Genes
OPTNMFN2HDAC6PRKN