| Name | branched-chain alpha-keto acid dehydrogenase activity |
| ID | GO_0047101 |
| collection_id | Molecular function |
| Description | Catalysis of the reaction: [a branched-chain alpha-keto acid] + CoA + NAD+ = [a branched-chain acyl-CoA] + CO2 + NADH. This enzyme system catalyzes the oxidative decarboxylation of branched-chain alpha-keto acids derived from L-leucine, L-isoleucine, and L-valine to branched-chain acyl-CoAs. |
| Related synonym | 2-oxoisovalerate dehydrogenase activity, 3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating) |
| External URL | |
| Genes |