negative regulation of mitotic metaphase/anaphase transition

I. Literature review

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Namenegative regulation of mitotic metaphase/anaphase transition
IDGO_0045841
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Biological process

Exact synonym

down regulation of mitotic metaphase/anaphase transition, down-regulation of mitotic metaphase/anaphase transition, downregulation of mitotic metaphase/anaphase transition

Description

Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.

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Genes