calcitriol biosynthetic process from calciol

I. Literature review

[source]
Namecalcitriol biosynthetic process from calciol
IDGO_0036378
collection_id

Biological process

Exact synonym

calcitriol biosynthesis from calciol, vitamin D3 activation

Description

Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol.

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Genes