mitotic checkpoint complex

I. Literature review

[source]
Namemitotic checkpoint complex
IDGO_0033597
collection_id

Cellular component

Exact synonym

MCC

Description

A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20.

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Genes