DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

I. Literature review

[source]
NameDNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
IDGO_0003918
collection_id

Molecular function

Alternative ID

GO:0061505

Exact synonym

DNA topoisomerase type II activity

Description

Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2.

Related synonym

DNA topoisomerase (ATP-hydrolysing), type II DNA topoisomerase activity

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Genes