| Name | DNA topoisomerase type I (single strand cut, ATP-independent) activity |
| ID | GO_0003917 |
| collection_id | Molecular function |
| Exact synonym | type I DNA topoisomerase activity, type I topoisomerase activity |
| Description | Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle. |
| Related synonym | nicking-closing enzyme activity, omega-protein activity, relaxing enzyme activity, swivelase activity, untwisting enzyme activity |
| Comment | Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity. |
| External URL | |
| Genes |