MAML1-RBP-Jkappa- ICN1 complex

I. Literature review

[source]
NameMAML1-RBP-Jkappa- ICN1 complex
IDGO_0002193
collection_id

Cellular component

Exact synonym

MAML1-CSL-ICN1, MAML1-CSL-Notch1 complex, MAML1-RBP-Jkappa-Notch1 complex

Description

A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-1 (MAML1); the complex is involved in transcriptional activation in response to Notch-mediated signaling.

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Genes