Biological process

promoter clearance from RNA polymerase II promoter, promoter escape from RNA polymerase II promoter, promoter-paused RNA polymerase II release

A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase II, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.