ZP1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ZP1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZP1 at tissue level.

III. Associated gene sets

GO_0007339Biological processbinding of sperm to zona pellucida
GO_0060468Biological processprevention of polyspermy
GO_0035805Cellular componentegg coat
GO_0005576Cellular componentextracellular region
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0005886Cellular componentplasma membrane
GO_0035804Molecular functionstructural constituent of egg coat
GO_0005515Molecular functionprotein binding
GO_0032190Molecular functionacrosin binding

IV. Literature review

[source]
Gene nameZP1
Protein nameZona pellucida glycoprotein 1
Truncated zona pellucida glycoprotein 1
Zona pellucida sperm-binding protein 1 (Zona pellucida glycoprotein 1) (Zp-1) [Cleaved into: Processed zona pellucida sperm-binding protein 1]
ZP1 protein
Synonyms
DescriptionFUNCTION: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida.

AccessionsA0A023ZYH6
ENST00000540908.1
H0YG11
Q6NVU7
P60852
ENST00000278853.10