I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 34% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 34% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 26% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 2217.18 | 245 / 245 | 100% | 18.42 | 502 / 502 |
| brain | 100% | 862.09 | 2634 / 2642 | 100% | 9.21 | 704 / 705 |
| thymus | 100% | 1234.64 | 653 / 653 | 99% | 9.43 | 601 / 605 |
| breast | 100% | 1061.68 | 459 / 459 | 99% | 9.28 | 1110 / 1118 |
| adrenal gland | 100% | 2019.79 | 258 / 258 | 99% | 8.63 | 228 / 230 |
| bladder | 100% | 873.95 | 21 / 21 | 99% | 13.06 | 497 / 504 |
| pancreas | 100% | 1658.58 | 328 / 328 | 98% | 8.12 | 175 / 178 |
| lung | 100% | 967.47 | 577 / 578 | 98% | 6.66 | 1135 / 1155 |
| esophagus | 100% | 938.65 | 1445 / 1445 | 98% | 8.59 | 179 / 183 |
| uterus | 100% | 1170.48 | 170 / 170 | 97% | 7.97 | 446 / 459 |
| kidney | 100% | 804.67 | 89 / 89 | 97% | 7.78 | 873 / 901 |
| stomach | 100% | 847.97 | 359 / 359 | 97% | 6.17 | 277 / 286 |
| intestine | 100% | 918.30 | 966 / 966 | 96% | 6.71 | 508 / 527 |
| ovary | 100% | 1129.52 | 180 / 180 | 96% | 5.74 | 413 / 430 |
| skin | 100% | 1265.11 | 1809 / 1809 | 86% | 6.71 | 404 / 472 |
| liver | 92% | 360.62 | 209 / 226 | 55% | 2.72 | 225 / 406 |
| adipose | 100% | 974.94 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 848.08 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 9.57 | 1 / 1 |
| blood vessel | 100% | 847.83 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 677.52 | 851 / 861 | 0% | 0 | 0 / 0 |
| muscle | 97% | 424.66 | 777 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 5.09 | 43 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 4.87 | 27 / 29 |
| eye | 0% | 0 | 0 / 0 | 54% | 2.65 | 43 / 80 |
| peripheral blood | 52% | 288.66 | 486 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006974 | Biological process | DNA damage response |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0003684 | Molecular function | damaged DNA binding |
| GO_0030674 | Molecular function | protein-macromolecule adaptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | ZNF432 |
| Protein name | Zinc finger protein 432 |
| Synonyms | KIAA0798 |
| Description | FUNCTION: Homologous recombination repressor that functions as a poly(ADP-ribose) (PAR) reader regulating DNA damage response and PARP inhibition. Once recruited to DNA lesions via DNA-, in a PAR-dependent mechanism, stimulates PARP1 activity . Binds preferentially ssDNA and inhibits EXO1-mediated resection, probably through a PAR-independent DNA-binding mechanism . . |
| Accessions | M0QZ71 ENST00000597273.1 M0R258 ENST00000594154.5 ENST00000598745.5 M0R0E2 ENST00000601310.1 O94892 ENST00000221315.10 M0R0H8 ENST00000600368.5 |
