ZNF365 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte	11 studies	38% ± 12%	Explore
oligodendrocyte precursor cell	11 studies	35% ± 18%	Explore
glutamatergic neuron	7 studies	48% ± 19%	Explore
astrocyte	4 studies	25% ± 7%	Explore
GABAergic neuron	3 studies	31% ± 7%	Explore

Name	Number of supported studies	Average coverage
brain	8 studies	40% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	3664.17	2641 / 2642	99%	16.06	701 / 705
ureter	0%	0	0 / 0	100%	1.03	1 / 1
prostate	40%	149.88	98 / 245	55%	1.10	277 / 502
esophagus	40%	547.46	575 / 1445	48%	3.07	88 / 183
pancreas	0%	1.17	1 / 328	86%	4.89	153 / 178
adrenal gland	6%	31.76	16 / 258	77%	13.40	177 / 230
breast	2%	5.86	9 / 459	73%	2.46	811 / 1118
lung	30%	105.37	173 / 578	42%	1.31	481 / 1155
blood vessel	60%	263.61	804 / 1335	0%	0	0 / 0
skin	12%	43.78	221 / 1809	42%	3.34	197 / 472
uterus	1%	5.00	1 / 170	46%	2.30	212 / 459
thymus	1%	1.89	4 / 653	42%	0.80	256 / 605
tonsil	0%	0	0 / 0	40%	1.16	18 / 45
bladder	0%	0	0 / 21	37%	2.31	184 / 504
kidney	1%	9.40	1 / 89	23%	0.64	209 / 901
ovary	0%	0	0 / 180	21%	0.35	92 / 430
heart	16%	56.03	134 / 861	0%	0	0 / 0
intestine	0%	0	0 / 966	9%	0.42	49 / 527
lymph node	0%	0	0 / 0	7%	0.10	2 / 29
stomach	1%	1.89	2 / 359	5%	0.13	14 / 286
eye	0%	0	0 / 0	4%	0.17	3 / 80
spleen	4%	12.32	9 / 241	0%	0	0 / 0
liver	0%	0	0 / 226	3%	0.12	11 / 406
peripheral blood	1%	6.18	13 / 929	0%	0	0 / 0
adipose	1%	3.30	11 / 1204	0%	0	0 / 0
muscle	0%	0.70	2 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0033566	Biological process	gamma-tubulin complex localization
GO_0010569	Biological process	regulation of double-strand break repair via homologous recombination
GO_0010975	Biological process	regulation of neuron projection development
GO_0021687	Biological process	cerebellar molecular layer morphogenesis
GO_0000723	Biological process	telomere maintenance
GO_0010977	Biological process	negative regulation of neuron projection development
GO_0000281	Biological process	mitotic cytokinesis
GO_0048714	Biological process	positive regulation of oligodendrocyte differentiation
GO_0140059	Biological process	dendrite arborization
GO_0110026	Biological process	regulation of DNA strand resection involved in replication fork processing
GO_0060997	Biological process	dendritic spine morphogenesis
GO_0005813	Cellular component	centrosome
GO_0005737	Cellular component	cytoplasm
GO_0042803	Molecular function	protein homodimerization activity
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

Gene name	ZNF365
Protein name	Protein ZNF365 (DISC1-binding zinc-finger protein) (Protein su48) Zinc finger protein 365 ZNF365 protein Talanin
Synonyms	DBZ KIAA0844
Description	FUNCTION: May play a role in uric acid excretion. FUNCTION: Involved in the regulation of neurogenesis. Negatively regulates neurite outgrowth . Involved in the morphogenesis of basket cells in the somatosensory cortex during embryogenesis. Involved in the positive regulation of oligodendrocyte differentiation during postnatal growth. Involved in dendritic arborization, morphogenesis of spine density dendrite, and establishment of postsynaptic dendrite density in cortical pyramidal neurons (By similarity). Involved in homologous recombination (HR) repair pathway. Required for proper resolution of DNA double-strand breaks (DSBs) by HR. Is required for recovery of stalled replication forks, and directly contributes to genomic stability. Interacts with PARP1 and mediates MRE11-dependent DNA end resection during replication fork recovery . Contributes to genomic stability by preventing telomere dysfunction . .
Accessions	Q70YC5 C9J1G1 Q70YC4 ENST00000395255.7 [Q70YC5-2] ENST00000395254.8 [Q70YC5-1] ENST00000421210.1 Q08ER3 Q495P1

ZNF365 report