Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 6 studies | 20% ± 5% | |
| epithelial cell | 5 studies | 31% ± 11% | |
| classical monocyte | 4 studies | 25% ± 6% | |
| mast cell | 4 studies | 22% ± 3% | |
| hematopoietic precursor cell | 3 studies | 18% ± 3% | |
| plasmacytoid dendritic cell | 3 studies | 17% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 5828.13 | 1445 / 1445 | 100% | 49.69 | 183 / 183 |
| ovary | 100% | 4766.19 | 180 / 180 | 100% | 32.10 | 430 / 430 |
| lung | 100% | 5619.26 | 578 / 578 | 100% | 45.37 | 1154 / 1155 |
| breast | 100% | 5737.16 | 459 / 459 | 100% | 56.48 | 1117 / 1118 |
| brain | 100% | 4881.08 | 2634 / 2642 | 100% | 55.50 | 705 / 705 |
| prostate | 100% | 4663.84 | 245 / 245 | 100% | 40.83 | 500 / 502 |
| uterus | 100% | 5381.17 | 170 / 170 | 100% | 46.49 | 457 / 459 |
| bladder | 100% | 5833.95 | 21 / 21 | 99% | 39.37 | 501 / 504 |
| pancreas | 100% | 2729.64 | 327 / 328 | 99% | 39.41 | 177 / 178 |
| intestine | 100% | 6599.02 | 966 / 966 | 99% | 39.03 | 522 / 527 |
| thymus | 100% | 5292.12 | 653 / 653 | 99% | 42.73 | 598 / 605 |
| stomach | 100% | 4021.03 | 359 / 359 | 99% | 37.16 | 282 / 286 |
| kidney | 100% | 3701.21 | 89 / 89 | 98% | 40.21 | 887 / 901 |
| skin | 100% | 7051.91 | 1809 / 1809 | 98% | 50.45 | 461 / 472 |
| liver | 99% | 2419.06 | 224 / 226 | 96% | 24.37 | 389 / 406 |
| adrenal gland | 100% | 4808.71 | 258 / 258 | 94% | 27.72 | 217 / 230 |
| adipose | 100% | 6046.67 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 6328.63 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 33.07 | 29 / 29 |
| muscle | 100% | 7266.84 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4700.01 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 53.72 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 15.23 | 1 / 1 |
| heart | 96% | 3677.30 | 830 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 95% | 23.91 | 76 / 80 |
| peripheral blood | 91% | 3444.59 | 848 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007250 | Biological process | activation of NF-kappaB-inducing kinase activity |
| GO_0070534 | Biological process | protein K63-linked ubiquitination |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | ZFP91 |
| Protein name | E3 ubiquitin-protein ligase ZFP91 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ZFP91) (Zinc finger protein 757) (Zinc finger protein 91 homolog) (Zfp-91) |
| Synonyms | ZNF757 FKSG11 |
| Description | FUNCTION: Atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis. . |
| Accessions | ENST00000316059.7 [Q96JP5-1] Q96JP5 |
