ZC3H4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0110064Biological processlncRNA catabolic process
GO_0140744Biological processnegative regulation of lncRNA transcription
GO_0006353Biological processDNA-templated transcription termination
GO_0032785Biological processnegative regulation of DNA-templated transcription, elongation
GO_0071027Biological processnuclear RNA surveillance
GO_0005694Cellular componentchromosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_1990841Molecular functionpromoter-specific chromatin binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameZC3H4
Protein nameZinc finger CCCH-type containing 4
Zinc finger CCCH domain-containing protein 4
SynonymsKIAA1064
C19orf7
DescriptionFUNCTION: RNA-binding protein that suppresses transcription of long non-coding RNAs (lncRNAs) . LncRNAs are defined as transcripts more than 200 nucleotides that are not translated into protein . Together with WDR82, part of a transcription termination checkpoint that promotes transcription termination of lncRNAs and their subsequent degradation by the exosome . The transcription termination checkpoint is activated by the inefficiently spliced first exon of lncRNAs . .

AccessionsM0QY97
ENST00000601973.1
ENST00000253048.10
Q9UPT8