ZC3H12D report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZC3H12D at tissue level.

III. Associated gene sets

GO_0061158Biological process3'-UTR-mediated mRNA destabilization
GO_0000932Cellular componentP-body
GO_0005654Cellular componentnucleoplasm
GO_0036464Cellular componentcytoplasmic ribonucleoprotein granule
GO_0005634Cellular componentnucleus
GO_0004521Molecular functionRNA endonuclease activity
GO_0005515Molecular functionprotein binding
GO_0003729Molecular functionmRNA binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameZC3H12D
Protein nameZinc finger CCCH-type containing 12D
Probable ribonuclease ZC3H12D (EC 3.1.-.-) (MCP-induced protein 4) (Transformed follicular lymphoma) (Zinc finger CCCH domain-containing protein 12D) (p34)
SynonymsMCPIP4
C6orf95
TFL
DescriptionFUNCTION: May regulate cell growth likely by suppressing RB1 phosphorylation . May function as RNase and regulate the levels of target RNA species (Potential). In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages . Serve as a tumor suppressor in certain leukemia cells . Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation . .

AccessionsENST00000458251.1
H0Y4Y6
B7ZBA4
ENST00000409806.8 [A2A288-1]
ENST00000409948.1
A2A288