Insufficient scRNA-seq data for expression of ZBED2 at single-cell level.
Insufficient scRNA-seq data for expression of ZBED2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 4387.99 | 652 / 653 | 100% | 240.38 | 602 / 605 |
| lung | 94% | 496.25 | 541 / 578 | 54% | 7.90 | 626 / 1155 |
| ureter | 0% | 0 | 0 / 0 | 100% | 6.64 | 1 / 1 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 31.69 | 28 / 29 |
| ovary | 2% | 1.68 | 3 / 180 | 88% | 39.10 | 378 / 430 |
| tonsil | 0% | 0 | 0 / 0 | 87% | 17.22 | 39 / 45 |
| esophagus | 38% | 428.65 | 548 / 1445 | 47% | 12.08 | 86 / 183 |
| skin | 52% | 116.75 | 935 / 1809 | 28% | 2.94 | 132 / 472 |
| pancreas | 0% | 0.60 | 1 / 328 | 47% | 7.65 | 84 / 178 |
| uterus | 4% | 31.06 | 6 / 170 | 44% | 6.99 | 200 / 459 |
| bladder | 0% | 0 | 0 / 21 | 28% | 7.45 | 143 / 504 |
| kidney | 7% | 7.99 | 6 / 89 | 15% | 1.79 | 135 / 901 |
| intestine | 6% | 10.81 | 60 / 966 | 12% | 2.30 | 65 / 527 |
| peripheral blood | 18% | 60.57 | 165 / 929 | 0% | 0 | 0 / 0 |
| breast | 0% | 0.13 | 1 / 459 | 14% | 1.16 | 155 / 1118 |
| stomach | 1% | 1.00 | 3 / 359 | 9% | 1.88 | 27 / 286 |
| brain | 9% | 17.33 | 237 / 2642 | 0% | 0.06 | 2 / 705 |
| spleen | 6% | 4.64 | 15 / 241 | 0% | 0 | 0 / 0 |
| adipose | 4% | 4.64 | 49 / 1204 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 3% | 0.19 | 13 / 406 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.13 | 2 / 80 |
| prostate | 1% | 0.66 | 2 / 245 | 2% | 0.16 | 8 / 502 |
| adrenal gland | 0% | 0 | 0 / 258 | 1% | 0.12 | 2 / 230 |
| blood vessel | 1% | 0.53 | 7 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.18 | 2 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0045618 | Biological process | positive regulation of keratinocyte differentiation |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0000976 | Molecular function | transcription cis-regulatory region binding |
| Gene name | ZBED2 |
| Protein name | Zinc finger BED domain-containing protein 2 |
| Synonyms | |
| Description | FUNCTION: Transcriptional regulator which has intrinsic repressor activity and which competes with the transcriptional activator IRF1 for binding to the 5'-[CA]GAA[AC]C[CT]-3' consensus sequence in gene promoters . May thereby play a role in keratinocyte differentiation . . |
| Accessions | ENST00000317012.5 Q9BTP6 |