YBX2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of YBX2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of YBX2 at tissue level.

III. Associated gene sets

GO_0006366Biological processtranscription by RNA polymerase II
GO_0048599Biological processoocyte development
GO_0010468Biological processregulation of gene expression
GO_0007283Biological processspermatogenesis
GO_0009386Biological processtranslational attenuation
GO_0120162Biological processpositive regulation of cold-induced thermogenesis
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0003676Molecular functionnucleic acid binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameYBX2
Protein nameY-box-binding protein 2 (Contrin) (DNA-binding protein C) (Dbpc) (Germ cell-specific Y-box-binding protein) (MSY2 homolog)
Alternative protein YBX2
Y-box binding protein 2
SynonymsMSY2
CSDA3
DescriptionFUNCTION: Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full-length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay (By similarity). .

AccessionsENST00000007699.10
L8EAU5
ENST00000571464.1
I3L2D6
Q9Y2T7
ENST00000672150.1