Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 4 studies | 37% ± 13% | |
| astrocyte | 4 studies | 23% ± 3% | |
| glutamatergic neuron | 4 studies | 43% ± 13% | |
| oligodendrocyte | 4 studies | 21% ± 3% | |
| endothelial cell | 3 studies | 18% ± 3% | |
| epithelial cell | 3 studies | 30% ± 10% | |
| oligodendrocyte precursor cell | 3 studies | 24% ± 4% | |
| dendritic cell | 3 studies | 21% ± 1% | |
| interneuron | 3 studies | 40% ± 18% | |
| neuron | 3 studies | 22% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 621.33 | 1445 / 1445 | 100% | 23.20 | 183 / 183 |
| ovary | 100% | 636.22 | 180 / 180 | 100% | 30.86 | 430 / 430 |
| stomach | 100% | 520.12 | 359 / 359 | 100% | 26.02 | 286 / 286 |
| breast | 100% | 809.23 | 459 / 459 | 100% | 28.23 | 1117 / 1118 |
| bladder | 100% | 693.67 | 21 / 21 | 100% | 30.24 | 503 / 504 |
| prostate | 100% | 585.38 | 245 / 245 | 100% | 19.32 | 501 / 502 |
| uterus | 100% | 693.17 | 170 / 170 | 100% | 28.21 | 458 / 459 |
| kidney | 100% | 509.35 | 89 / 89 | 100% | 17.27 | 898 / 901 |
| intestine | 100% | 633.58 | 966 / 966 | 100% | 29.79 | 525 / 527 |
| skin | 100% | 937.03 | 1809 / 1809 | 100% | 23.19 | 470 / 472 |
| thymus | 100% | 556.26 | 653 / 653 | 99% | 17.45 | 601 / 605 |
| lung | 99% | 514.46 | 574 / 578 | 100% | 26.74 | 1155 / 1155 |
| pancreas | 100% | 390.91 | 327 / 328 | 99% | 21.07 | 177 / 178 |
| brain | 98% | 430.03 | 2598 / 2642 | 100% | 13.69 | 705 / 705 |
| adrenal gland | 100% | 740.02 | 258 / 258 | 98% | 17.31 | 226 / 230 |
| liver | 99% | 436.75 | 224 / 226 | 97% | 13.36 | 394 / 406 |
| adipose | 100% | 763.99 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 34.94 | 29 / 29 |
| muscle | 100% | 538.17 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 701.77 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 26.17 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 25.27 | 1 / 1 |
| blood vessel | 100% | 478.49 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 20.54 | 79 / 80 |
| heart | 97% | 451.56 | 835 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 89% | 536.71 | 829 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006412 | Biological process | translation |
| GO_0043039 | Biological process | tRNA aminoacylation |
| GO_0070184 | Biological process | mitochondrial tyrosyl-tRNA aminoacylation |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005829 | Cellular component | cytosol |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0000049 | Molecular function | tRNA binding |
| GO_0072545 | Molecular function | L-tyrosine binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0004831 | Molecular function | tyrosine-tRNA ligase activity |
| GO_0005524 | Molecular function | ATP binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | YARS2 |
| Protein name | Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) Tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) |
| Synonyms | CGI-04 |
| Description | FUNCTION: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). . |
| Accessions | ENST00000548490.1 Q9Y2Z4 H0YHS6 ENST00000324868.13 |