YARS2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006412Biological processtranslation
GO_0043039Biological processtRNA aminoacylation
GO_0070184Biological processmitochondrial tyrosyl-tRNA aminoacylation
GO_0005739Cellular componentmitochondrion
GO_0016604Cellular componentnuclear body
GO_0005829Cellular componentcytosol
GO_0005759Cellular componentmitochondrial matrix
GO_0042803Molecular functionprotein homodimerization activity
GO_0000049Molecular functiontRNA binding
GO_0072545Molecular functionL-tyrosine binding
GO_0005515Molecular functionprotein binding
GO_0004831Molecular functiontyrosine-tRNA ligase activity
GO_0005524Molecular functionATP binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameYARS2
Protein nameTyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase)
Tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)
SynonymsCGI-04
DescriptionFUNCTION: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). .

AccessionsENST00000548490.1
Q9Y2Z4
H0YHS6
ENST00000324868.13