I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 10 studies | 30% ± 12% | |
| ciliated cell | 6 studies | 28% ± 9% | |
| oligodendrocyte precursor cell | 4 studies | 27% ± 10% | |
| astrocyte | 3 studies | 31% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 10 studies | 30% ± 12% | |
| ciliated cell | 6 studies | 28% ± 9% | |
| oligodendrocyte precursor cell | 4 studies | 27% ± 10% | |
| astrocyte | 3 studies | 31% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 35% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 3269.70 | 245 / 245 | 99% | 12.49 | 496 / 502 |
| adrenal gland | 100% | 18457.76 | 258 / 258 | 98% | 35.80 | 226 / 230 |
| brain | 99% | 2459.53 | 2612 / 2642 | 95% | 10.96 | 671 / 705 |
| thymus | 100% | 2587.56 | 652 / 653 | 92% | 8.66 | 554 / 605 |
| ovary | 100% | 4386.01 | 180 / 180 | 87% | 7.92 | 374 / 430 |
| pancreas | 100% | 1576.18 | 328 / 328 | 85% | 7.03 | 152 / 178 |
| uterus | 99% | 5731.52 | 169 / 170 | 85% | 10.20 | 390 / 459 |
| breast | 88% | 1337.48 | 404 / 459 | 96% | 13.73 | 1074 / 1118 |
| kidney | 100% | 1479.90 | 89 / 89 | 83% | 7.64 | 745 / 901 |
| skin | 79% | 1308.87 | 1430 / 1809 | 99% | 21.62 | 466 / 472 |
| esophagus | 98% | 1622.62 | 1413 / 1445 | 79% | 7.75 | 145 / 183 |
| intestine | 98% | 2020.98 | 951 / 966 | 74% | 5.98 | 392 / 527 |
| lung | 88% | 1085.33 | 507 / 578 | 78% | 6.88 | 896 / 1155 |
| bladder | 100% | 1276.81 | 21 / 21 | 64% | 4.42 | 321 / 504 |
| stomach | 96% | 1205.33 | 345 / 359 | 63% | 4.90 | 179 / 286 |
| liver | 59% | 394.50 | 133 / 226 | 58% | 4.02 | 235 / 406 |
| eye | 0% | 0 | 0 / 0 | 100% | 29.52 | 80 / 80 |
| spleen | 100% | 5195.34 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 87% | 8.94 | 39 / 45 |
| adipose | 85% | 829.17 | 1024 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 76% | 10.56 | 22 / 29 |
| heart | 48% | 534.22 | 411 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 25% | 295.64 | 231 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 18% | 142.11 | 246 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 0% | 1.78 | 3 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007605 | Biological process | sensory perception of sound |
| GO_0021694 | Biological process | cerebellar Purkinje cell layer formation |
| GO_0001895 | Biological process | retina homeostasis |
| GO_1990227 | Biological process | paranodal junction maintenance |
| GO_0045184 | Biological process | establishment of protein localization |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0060088 | Biological process | auditory receptor cell stereocilium organization |
| GO_0060122 | Biological process | inner ear receptor cell stereocilium organization |
| GO_0051649 | Biological process | establishment of localization in cell |
| GO_0050953 | Biological process | sensory perception of light stimulus |
| GO_0060113 | Biological process | inner ear receptor cell differentiation |
| GO_0050910 | Biological process | detection of mechanical stimulus involved in sensory perception of sound |
| GO_1990075 | Cellular component | periciliary membrane compartment |
| GO_0032420 | Cellular component | stereocilium |
| GO_0032391 | Cellular component | photoreceptor connecting cilium |
| GO_0002141 | Cellular component | stereocilia ankle link |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0002142 | Cellular component | stereocilia ankle link complex |
| GO_0001917 | Cellular component | photoreceptor inner segment |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0005884 | Cellular component | actin filament |
| GO_0005929 | Cellular component | cilium |
| GO_0045202 | Cellular component | synapse |
| GO_0032426 | Cellular component | stereocilium tip |
| GO_0030426 | Cellular component | growth cone |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0036064 | Cellular component | ciliary basal body |
| GO_1990696 | Cellular component | USH2 complex |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | WHRN |
| Protein name | Whirlin (Autosomal recessive deafness type 31 protein) Whirlin DFNB31 protein |
| Synonyms | DFNB31 KIAA1526 |
| Description | FUNCTION: Involved in hearing and vision as member of the USH2 complex. Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear. Involved in the maintenance of the hair bundle ankle region, which connects stereocilia in cochlear hair cells of the inner ear. In retina photoreceptors, required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport. . |
| Accessions | ENST00000362057.4 [Q9P202-1] B9EGE6 ENST00000674036.8 A0A8V8TQ31 Q9P202 ENST00000699486.1 ENST00000265134.10 [Q9P202-3] A0A669KBA5 A0A8V8TNT0 A0A669KBJ1 ENST00000699485.1 ENST00000374057.3 [Q9P202-2] ENST00000673697.1 |
