WASF1 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	11 studies	58% ± 24%	Explore
oligodendrocyte precursor cell	11 studies	26% ± 7%	Explore
oligodendrocyte	9 studies	24% ± 10%	Explore
GABAergic neuron	8 studies	38% ± 19%	Explore
neuron	6 studies	34% ± 9%	Explore
interneuron	6 studies	40% ± 13%	Explore
endothelial cell	4 studies	34% ± 17%	Explore
GABAergic interneuron	3 studies	23% ± 5%	Explore
granule cell	3 studies	32% ± 15%	Explore
precursor B cell	3 studies	40% ± 10%	Explore
retina horizontal cell	3 studies	21% ± 4%	Explore

Name	Number of supported studies	Average coverage
brain	14 studies	35% ± 20%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	99%	7477.55	2611 / 2642	100%	83.06	702 / 705
ovary	100%	2634.82	180 / 180	92%	24.51	394 / 430
adrenal gland	91%	865.64	236 / 258	94%	41.97	216 / 230
uterus	98%	1460.06	166 / 170	86%	27.73	396 / 459
esophagus	97%	1310.84	1405 / 1445	80%	17.78	146 / 183
breast	91%	996.79	417 / 459	68%	11.33	760 / 1118
prostate	73%	648.48	178 / 245	84%	10.57	422 / 502
kidney	70%	684.15	62 / 89	87%	16.25	783 / 901
skin	79%	1224.54	1422 / 1809	77%	13.55	363 / 472
bladder	86%	772.81	18 / 21	66%	11.75	333 / 504
lung	59%	469.73	340 / 578	73%	19.39	840 / 1155
intestine	75%	1162.36	720 / 966	46%	5.51	245 / 527
thymus	44%	330.03	285 / 653	55%	5.99	330 / 605
adipose	92%	1020.18	1113 / 1204	0%	0	0 / 0
liver	41%	281.74	92 / 226	51%	7.38	207 / 406
tonsil	0%	0	0 / 0	84%	15.95	38 / 45
pancreas	13%	88.76	41 / 328	71%	9.52	126 / 178
stomach	38%	843.50	138 / 359	44%	6.48	125 / 286
blood vessel	79%	752.66	1051 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	45%	4.37	36 / 80
lymph node	0%	0	0 / 0	21%	2.32	6 / 29
heart	8%	58.99	73 / 861	0%	0	0 / 0
peripheral blood	8%	76.78	74 / 929	0%	0	0 / 0
spleen	6%	41.55	15 / 241	0%	0	0 / 0
muscle	1%	9.14	11 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0072673	Biological process	lamellipodium morphogenesis
GO_0006898	Biological process	receptor-mediated endocytosis
GO_1990416	Biological process	cellular response to brain-derived neurotrophic factor stimulus
GO_0097484	Biological process	dendrite extension
GO_0051388	Biological process	positive regulation of neurotrophin TRK receptor signaling pathway
GO_0030041	Biological process	actin filament polymerization
GO_0065003	Biological process	protein-containing complex assembly
GO_0030036	Biological process	actin cytoskeleton organization
GO_0007005	Biological process	mitochondrion organization
GO_0098885	Biological process	modification of postsynaptic actin cytoskeleton
GO_0016601	Biological process	Rac protein signal transduction
GO_2000601	Biological process	positive regulation of Arp2/3 complex-mediated actin nucleation
GO_0005856	Cellular component	cytoskeleton
GO_0032991	Cellular component	protein-containing complex
GO_0098794	Cellular component	postsynapse
GO_0005925	Cellular component	focal adhesion
GO_0015629	Cellular component	actin cytoskeleton
GO_0005829	Cellular component	cytosol
GO_0005741	Cellular component	mitochondrial outer membrane
GO_0030027	Cellular component	lamellipodium
GO_0031209	Cellular component	SCAR complex
GO_0034237	Molecular function	protein kinase A regulatory subunit binding
GO_0071933	Molecular function	Arp2/3 complex binding
GO_0031267	Molecular function	small GTPase binding
GO_0051018	Molecular function	protein kinase A binding
GO_0005515	Molecular function	protein binding
GO_0003779	Molecular function	actin binding

Gene name	WASF1
Protein name	WASP family member 1 Actin-binding protein WASF1 (Protein WAVE-1) (Verprolin homology domain-containing protein 1) (Wiskott-Aldrich syndrome protein family member 1) (WASP family protein member 1)
Synonyms	KIAA0269 SCAR1 WAVE1
Description	FUNCTION: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation . The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). Also involved in the regulation of mitochondrial dynamics . .
Accessions	ENST00000392586.5 Q92558 ENST00000392589.6 Q5SZK3 ENST00000368938.5 ENST00000447287.5 ENST00000359451.6 ENST00000444391.5 Q5SZK5 ENST00000392588.5 Q5SZK4 ENST00000265601.7 ENST00000419252.1 ENST00000392587.6

WASF1 report