Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 7 studies | 22% ± 6% | |
epithelial cell | 6 studies | 29% ± 12% | |
microglial cell | 4 studies | 19% ± 4% | |
astrocyte | 4 studies | 28% ± 11% | |
glutamatergic neuron | 4 studies | 48% ± 17% | |
oligodendrocyte precursor cell | 4 studies | 25% ± 6% | |
oligodendrocyte | 4 studies | 23% ± 6% | |
myeloid cell | 3 studies | 17% ± 1% | |
natural killer cell | 3 studies | 16% ± 0% | |
ciliated cell | 3 studies | 29% ± 5% | |
abnormal cell | 3 studies | 28% ± 9% | |
GABAergic neuron | 3 studies | 45% ± 3% | |
basal cell | 3 studies | 21% ± 5% | |
macrophage | 3 studies | 19% ± 2% | |
interneuron | 3 studies | 37% ± 18% | |
neuron | 3 studies | 24% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1787.39 | 1445 / 1445 | 100% | 30.36 | 183 / 183 |
intestine | 100% | 1738.33 | 966 / 966 | 100% | 23.91 | 527 / 527 |
ovary | 100% | 1279.30 | 180 / 180 | 100% | 22.64 | 430 / 430 |
uterus | 100% | 1484.89 | 170 / 170 | 100% | 26.51 | 459 / 459 |
breast | 100% | 1685.92 | 459 / 459 | 100% | 28.66 | 1117 / 1118 |
brain | 100% | 2039.89 | 2638 / 2642 | 100% | 28.99 | 705 / 705 |
bladder | 100% | 1702.76 | 21 / 21 | 100% | 23.86 | 503 / 504 |
prostate | 100% | 1378.04 | 245 / 245 | 100% | 18.18 | 501 / 502 |
stomach | 100% | 1164.92 | 359 / 359 | 100% | 25.13 | 285 / 286 |
thymus | 100% | 1362.72 | 653 / 653 | 99% | 16.55 | 600 / 605 |
lung | 99% | 1363.97 | 571 / 578 | 100% | 24.79 | 1155 / 1155 |
pancreas | 98% | 848.08 | 322 / 328 | 99% | 16.66 | 176 / 178 |
skin | 100% | 2580.59 | 1809 / 1809 | 97% | 19.74 | 458 / 472 |
kidney | 100% | 1469.31 | 89 / 89 | 96% | 16.32 | 868 / 901 |
liver | 100% | 1235.01 | 226 / 226 | 96% | 11.54 | 391 / 406 |
adrenal gland | 100% | 1673.02 | 258 / 258 | 96% | 11.87 | 221 / 230 |
adipose | 100% | 1734.69 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 18.42 | 29 / 29 |
muscle | 100% | 3106.56 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1537.35 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 25.95 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.52 | 1 / 1 |
blood vessel | 100% | 1645.04 | 1333 / 1335 | 0% | 0 | 0 / 0 |
heart | 96% | 1306.49 | 828 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 85% | 8.70 | 68 / 80 |
peripheral blood | 83% | 1443.19 | 769 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0015031 | Biological process | protein transport |
GO_0016236 | Biological process | macroautophagy |
GO_0032511 | Biological process | late endosome to vacuole transport via multivesicular body sorting pathway |
GO_0036258 | Biological process | multivesicular body assembly |
GO_0071985 | Biological process | multivesicular body sorting pathway |
GO_1904903 | Biological process | ESCRT III complex disassembly |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0010008 | Cellular component | endosome membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005771 | Cellular component | multivesicular body |
GO_0005515 | Molecular function | protein binding |
Gene name | VTA1 |
Protein name | Vacuolar protein sorting-associated protein VTA1 homolog (Dopamine-responsive gene 1 protein) (DRG-1) (LYST-interacting protein 5) (LIP5) (SKD1-binding protein 1) (SBP1) Vesicle trafficking 1 Chromosome 6 open reading frame 55, isoform CRA_b (Vesicle trafficking 1) |
Synonyms | HSPC228 C6orf55 hCG_18120 My012 |
Description | FUNCTION: Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding. . |
Accessions | ENST00000452973.6 [Q9NP79-2] A0A087WY55 Q9NP79 ENST00000367621.1 ENST00000367630.9 [Q9NP79-1] Q5TGM0 ENST00000620996.4 |