VPS37C report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006623Biological processprotein targeting to vacuole
GO_0016236Biological processmacroautophagy
GO_0039702Biological processviral budding via host ESCRT complex
GO_0036258Biological processmultivesicular body assembly
GO_0006612Biological processprotein targeting to membrane
GO_0043162Biological processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO_0043328Biological processprotein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO_0090148Biological processmembrane fission
GO_0010008Cellular componentendosome membrane
GO_0070062Cellular componentextracellular exosome
GO_0031902Cellular componentlate endosome membrane
GO_0000813Cellular componentESCRT I complex
GO_0048306Molecular functioncalcium-dependent protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameVPS37C
Protein nameVPS37C subunit of ESCRT-I
Vacuolar protein sorting-associated protein 37C (hVps37C) (ESCRT-I complex subunit VPS37C)
SynonymsPML39
DescriptionFUNCTION: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. .

FUNCTION: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. .

AccessionsF5H4Q5
ENST00000538036.1
A5D8V6
ENST00000301765.10