Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell of lymphatic vessel | 17 studies | 36% ± 10% | |
oligodendrocyte | 12 studies | 44% ± 23% | |
endothelial cell | 12 studies | 24% ± 7% | |
astrocyte | 10 studies | 39% ± 24% | |
microglial cell | 8 studies | 35% ± 24% | |
macrophage | 8 studies | 29% ± 10% | |
glutamatergic neuron | 7 studies | 39% ± 28% | |
adipocyte | 6 studies | 22% ± 6% | |
fibroblast | 6 studies | 25% ± 6% | |
oligodendrocyte precursor cell | 6 studies | 40% ± 16% | |
GABAergic neuron | 6 studies | 42% ± 28% | |
epithelial cell | 5 studies | 27% ± 9% | |
interneuron | 5 studies | 47% ± 31% | |
neuron | 4 studies | 42% ± 20% | |
retinal pigment epithelial cell | 4 studies | 28% ± 12% | |
lymphocyte | 3 studies | 25% ± 8% | |
dendritic cell | 3 studies | 19% ± 3% | |
abnormal cell | 3 studies | 25% ± 11% | |
ependymal cell | 3 studies | 29% ± 15% | |
alveolar macrophage | 3 studies | 24% ± 5% | |
monocyte | 3 studies | 22% ± 2% | |
pericyte | 3 studies | 21% ± 7% | |
transit amplifying cell | 3 studies | 29% ± 17% | |
myeloid cell | 3 studies | 25% ± 1% | |
smooth muscle cell | 3 studies | 18% ± 1% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 11 studies | 37% ± 25% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 3368.89 | 653 / 653 | 100% | 24.15 | 605 / 605 |
breast | 100% | 3036.61 | 459 / 459 | 100% | 25.55 | 1117 / 1118 |
skin | 100% | 2850.38 | 1807 / 1809 | 100% | 25.46 | 472 / 472 |
brain | 100% | 2856.23 | 2642 / 2642 | 100% | 30.66 | 704 / 705 |
kidney | 100% | 2720.17 | 89 / 89 | 100% | 22.29 | 899 / 901 |
prostate | 100% | 2509.79 | 245 / 245 | 100% | 17.27 | 500 / 502 |
adrenal gland | 100% | 3754.53 | 258 / 258 | 99% | 21.82 | 228 / 230 |
ovary | 100% | 3034.58 | 180 / 180 | 98% | 14.45 | 422 / 430 |
pancreas | 99% | 1251.32 | 325 / 328 | 98% | 15.42 | 175 / 178 |
lung | 100% | 2597.63 | 578 / 578 | 96% | 16.00 | 1104 / 1155 |
uterus | 100% | 3345.45 | 170 / 170 | 93% | 15.47 | 425 / 459 |
bladder | 100% | 2988.05 | 21 / 21 | 89% | 13.74 | 451 / 504 |
esophagus | 100% | 2843.89 | 1445 / 1445 | 84% | 10.88 | 154 / 183 |
stomach | 100% | 1913.92 | 359 / 359 | 77% | 8.47 | 221 / 286 |
intestine | 100% | 3011.50 | 966 / 966 | 77% | 8.31 | 406 / 527 |
liver | 98% | 1030.69 | 222 / 226 | 65% | 5.92 | 263 / 406 |
adipose | 100% | 3144.06 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3009.61 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 23.76 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 13.52 | 29 / 29 |
muscle | 100% | 1992.69 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2870.03 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 98% | 1706.18 | 840 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 95% | 1464.75 | 880 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 78% | 9.02 | 35 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0015031 | Biological process | protein transport |
GO_0032456 | Biological process | endocytic recycling |
GO_0006893 | Biological process | Golgi to plasma membrane transport |
GO_0005768 | Cellular component | endosome |
GO_0005886 | Cellular component | plasma membrane |
GO_0101003 | Cellular component | ficolin-1-rich granule membrane |
GO_0005515 | Molecular function | protein binding |
Gene name | VPS35L |
Protein name | VPS35 endosomal protein-sorting factor-like (Esophageal cancer-associated protein) VPS35 endosomal protein-sorting factor-like VPS35 endosomal protein sorting factor like |
Synonyms | hCG_1993553 101F10.2 C16orf62 MGC16824 |
Description | FUNCTION: Acts as a component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1) . The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes . In the endosomes, drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling . Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association with the CCC complex and cooperation with the WASH complex on early endosomes. Seems not to be required for CCC complex stability . .; FUNCTION: (Microbial infection) The heterotrimeric retriever complex, in collaboration with the CCC complex, mediates the exit of human papillomavirus to the cell surface. . |
Accessions | ENST00000543152.5 H3BNX2 ENST00000542263.5 ENST00000567245.5 H3BUS7 ENST00000251143.9 ENST00000539322.5 H3BTI5 ENST00000542027.3 F5H7K1 H3BVG8 F6S1J4 H3BV68 ENST00000417362.7 [Q7Z3J2-1] ENST00000537186.6 ENST00000513947.8 I3L1U5 Q7Z3J2 ENST00000544670.5 H0YFG6 ENST00000563649.1 E7EWW0 H3BRV8 ENST00000538552.5 |