I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| naive B cell | 6 studies | 22% ± 5% | |
| memory B cell | 4 studies | 19% ± 3% | |
| B cell | 3 studies | 20% ± 5% | |
| epithelial cell | 3 studies | 21% ± 6% | |
| glutamatergic neuron | 3 studies | 26% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| naive B cell | 6 studies | 22% ± 5% | |
| memory B cell | 4 studies | 19% ± 3% | |
| B cell | 3 studies | 20% ± 5% | |
| epithelial cell | 3 studies | 21% ± 6% | |
| glutamatergic neuron | 3 studies | 26% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 19% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 651.98 | 459 / 459 | 100% | 12.83 | 1118 / 1118 |
| esophagus | 100% | 651.16 | 1445 / 1445 | 100% | 16.66 | 183 / 183 |
| lung | 100% | 712.50 | 578 / 578 | 100% | 13.83 | 1155 / 1155 |
| ovary | 100% | 644.85 | 180 / 180 | 100% | 12.80 | 430 / 430 |
| thymus | 100% | 722.76 | 653 / 653 | 100% | 13.21 | 604 / 605 |
| bladder | 100% | 708.71 | 21 / 21 | 100% | 11.68 | 503 / 504 |
| prostate | 100% | 701.82 | 245 / 245 | 100% | 9.68 | 501 / 502 |
| uterus | 100% | 718.85 | 170 / 170 | 100% | 17.83 | 458 / 459 |
| pancreas | 100% | 377.09 | 327 / 328 | 100% | 12.68 | 178 / 178 |
| brain | 99% | 596.27 | 2617 / 2642 | 100% | 9.22 | 705 / 705 |
| intestine | 100% | 769.26 | 966 / 966 | 99% | 9.48 | 521 / 527 |
| kidney | 100% | 556.56 | 89 / 89 | 99% | 8.38 | 889 / 901 |
| stomach | 100% | 603.78 | 359 / 359 | 99% | 9.20 | 282 / 286 |
| liver | 100% | 404.46 | 226 / 226 | 98% | 6.09 | 399 / 406 |
| adrenal gland | 100% | 584.17 | 258 / 258 | 97% | 8.49 | 224 / 230 |
| skin | 100% | 729.03 | 1809 / 1809 | 96% | 9.42 | 454 / 472 |
| adipose | 100% | 614.09 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 19.05 | 29 / 29 |
| spleen | 100% | 1294.89 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 15.15 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.31 | 1 / 1 |
| blood vessel | 100% | 565.36 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 352.44 | 799 / 803 | 0% | 0 | 0 / 0 |
| heart | 99% | 367.45 | 851 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 93% | 710.28 | 868 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 86% | 5.97 | 69 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0018023 | Biological process | peptidyl-lysine trimethylation |
| GO_0032780 | Biological process | negative regulation of ATP-dependent activity |
| GO_0006338 | Biological process | chromatin remodeling |
| GO_0018022 | Biological process | peptidyl-lysine methylation |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0051117 | Molecular function | ATPase binding |
| GO_0042054 | Molecular function | histone methyltransferase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0016279 | Molecular function | protein-lysine N-methyltransferase activity |
| Gene name | VCPKMT |
| Protein name | Protein N-lysine methyltransferase METTL21D (EC 2.1.1.-) (Methyltransferase-like protein 21D) (VCP lysine methyltransferase) (VCP-KMT) (Valosin-containing protein lysine methyltransferase) |
| Synonyms | C14orf138 METTL21D |
| Description | FUNCTION: Protein N-lysine methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity. . |
| Accessions | Q9H867 ENST00000395860.7 [Q9H867-4] ENST00000491402.5 [Q9H867-1] ENST00000395859.2 [Q9H867-5] |
