I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 27% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 27% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 23% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1877.22 | 1445 / 1445 | 100% | 66.84 | 183 / 183 |
| lung | 100% | 2191.20 | 578 / 578 | 100% | 62.44 | 1154 / 1155 |
| breast | 100% | 2311.92 | 459 / 459 | 100% | 78.53 | 1116 / 1118 |
| brain | 100% | 1872.80 | 2638 / 2642 | 100% | 66.63 | 704 / 705 |
| stomach | 100% | 1494.66 | 359 / 359 | 100% | 59.21 | 285 / 286 |
| thymus | 100% | 1823.79 | 653 / 653 | 100% | 53.16 | 602 / 605 |
| skin | 100% | 2301.43 | 1809 / 1809 | 99% | 84.74 | 469 / 472 |
| prostate | 100% | 1735.67 | 244 / 245 | 100% | 59.57 | 500 / 502 |
| kidney | 100% | 2365.48 | 89 / 89 | 99% | 55.74 | 893 / 901 |
| liver | 100% | 1560.55 | 226 / 226 | 99% | 55.47 | 402 / 406 |
| bladder | 100% | 2012.52 | 21 / 21 | 99% | 58.62 | 499 / 504 |
| uterus | 100% | 1865.51 | 170 / 170 | 99% | 60.56 | 454 / 459 |
| intestine | 100% | 2011.57 | 966 / 966 | 99% | 56.77 | 521 / 527 |
| adrenal gland | 100% | 2497.83 | 258 / 258 | 99% | 47.77 | 227 / 230 |
| ovary | 100% | 1660.96 | 180 / 180 | 99% | 38.82 | 424 / 430 |
| pancreas | 98% | 962.29 | 323 / 328 | 99% | 47.05 | 176 / 178 |
| adipose | 100% | 2569.51 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3017.49 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 56.84 | 29 / 29 |
| spleen | 100% | 1711.75 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 57.90 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 34.69 | 1 / 1 |
| muscle | 100% | 1556.94 | 802 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 1178.41 | 835 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 96% | 1912.17 | 894 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 95% | 37.73 | 76 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0043308 | Biological process | eosinophil degranulation |
| GO_0017156 | Biological process | calcium-ion regulated exocytosis |
| GO_0006911 | Biological process | phagocytosis, engulfment |
| GO_1903595 | Biological process | positive regulation of histamine secretion by mast cell |
| GO_0016192 | Biological process | vesicle-mediated transport |
| GO_0006887 | Biological process | exocytosis |
| GO_0043312 | Biological process | neutrophil degranulation |
| GO_0008333 | Biological process | endosome to lysosome transport |
| GO_0043320 | Biological process | natural killer cell degranulation |
| GO_0015031 | Biological process | protein transport |
| GO_0006888 | Biological process | endoplasmic reticulum to Golgi vesicle-mediated transport |
| GO_0006906 | Biological process | vesicle fusion |
| GO_0097352 | Biological process | autophagosome maturation |
| GO_0031091 | Cellular component | platelet alpha granule |
| GO_0030667 | Cellular component | secretory granule membrane |
| GO_0031902 | Cellular component | late endosome membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0035577 | Cellular component | azurophil granule membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0030669 | Cellular component | clathrin-coated endocytic vesicle membrane |
| GO_0043005 | Cellular component | neuron projection |
| GO_0005802 | Cellular component | trans-Golgi network |
| GO_0045335 | Cellular component | phagocytic vesicle |
| GO_0045202 | Cellular component | synapse |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0030670 | Cellular component | phagocytic vesicle membrane |
| GO_0031143 | Cellular component | pseudopodium |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0030141 | Cellular component | secretory granule |
| GO_0030658 | Cellular component | transport vesicle membrane |
| GO_0030027 | Cellular component | lamellipodium |
| GO_0031201 | Cellular component | SNARE complex |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0000149 | Molecular function | SNARE binding |
| GO_0005484 | Molecular function | SNAP receptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | VAMP7 |
| Protein name | Vesicle-associated membrane protein 7 (VAMP-7) (Synaptobrevin-like protein 1) (Tetanus-insensitive VAMP) (Ti-VAMP) Vesicle associated membrane protein 7 |
| Synonyms | SYBL1 |
| Description | FUNCTION: Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation. . |
| Accessions | ENST00000286448.12 [P51809-1] E5RH06 ENST00000488344.6 ENST00000711265.1 [P51809-3] ENST00000711260.1 [P51809-1] P51809 ENST00000711262.1 ENST00000460621.6 [P51809-3] ENST00000711264.1 [P51809-2] ENST00000262640.11 [P51809-2] |
