UTP4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000462Biological processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO_0006355Biological processregulation of DNA-templated transcription
GO_0030490Biological processmaturation of SSU-rRNA
GO_0042274Biological processribosomal small subunit biogenesis
GO_0005730Cellular componentnucleolus
GO_0001650Cellular componentfibrillar center
GO_0005694Cellular componentchromosome
GO_0005654Cellular componentnucleoplasm
GO_0034455Cellular componentt-UTP complex
GO_0032040Cellular componentsmall-subunit processome
GO_0030686Cellular component90S preribosome
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameUTP4
Protein nameAlternative protein CIRH1A
U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (UTP4 small subunit processome component)
U3 small nucleolar RNA-associated protein 4 homolog (UTP4 small subunit processome component)
U3 small nucleolar RNA-associated protein 4 homolog
UTP4 small subunit processome component
SynonymsKIAA1988
cPERP-E
CIRH1A
DescriptionFUNCTION: Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted d Involved in SSU pre-rRNA processing at sites A', A0, 1 and 2b. Required for optimal pre-ribosomal RNA transcription by RNA polymerase . May be a transcriptional regulator . .; FUNCTION: (Microbial infection) Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5'-GGGACTTTCC-3' found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV. .

AccessionsENST00000567235.6
ENST00000633692.1
A0A0J9YX18
ENST00000631541.1
ENST00000631682.1
Q969X6
ENST00000567460.5
ENST00000352319.8 [Q969X6-2]
H3BSH7
A0A0J9YXV4
A0A0J9YWM9
ENST00000575702.3
ENST00000631675.1
A0A0J9YWK2
A0A0J9YXZ9
I3L4T9
ENST00000567500.1
ENST00000563094.5 [Q969X6-3]
J3KSI1
H3BRM8
J3KTR0
ENST00000566227.5
ENST00000563299.5
L0R599
H3BPD7
J3KSE6
ENST00000314423.12 [Q969X6-1]
ENST00000632079.1
ENST00000562237.5
ENST00000634106.1
ENST00000568448.1