UTP25 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of UTP25 at tissue level.

III. Associated gene sets

GO_0040019Biological processpositive regulation of embryonic development
GO_1902570Biological processprotein localization to nucleolus
GO_0048568Biological processembryonic organ development
GO_0000462Biological processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO_0031648Biological processprotein destabilization
GO_0030163Biological processprotein catabolic process
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0032040Cellular componentsmall-subunit processome
GO_0034511Molecular functionU3 snoRNA binding
GO_0019843Molecular functionrRNA binding
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameUTP25
Protein nameU3 small nucleolar RNA-associated protein 25 homolog (Digestive organ expansion factor homolog) (UTP25 small subunit processor component)
U3 small nucleolar RNA-associated protein 25 homolog (UTP25 small subunit processor component)
SynonymsC1orf107
DIEXF
DEF
DescriptionFUNCTION: Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing (By similarity). Essential for embryonic development in part through the regulation of p53 pathway. Controls the expansion growth of digestive organs and liver . Also involved in the sympathetic neuronal development (By similarity). Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53 . .

AccessionsENST00000491415.7
Q68CQ4
ENST00000457820.1
H7C2R4