UTP20 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000447Biological processendonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0006364Biological processrRNA processing
GO_0000480Biological processendonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO_0000472Biological processendonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO_0042274Biological processribosomal small subunit biogenesis
GO_0005730Cellular componentnucleolus
GO_0030686Cellular component90S preribosome
GO_0005654Cellular componentnucleoplasm
GO_0030688Cellular componentpreribosome, small subunit precursor
GO_0005886Cellular componentplasma membrane
GO_0032040Cellular componentsmall-subunit processome
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameUTP20
Protein nameSmall subunit processome component 20 homolog (Down-regulated in metastasis protein) (Novel nucleolar protein 73) (NNP73) (Protein Key-1A6)
SynonymsDRIM
DescriptionFUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in 18S pre-rRNA processing. Associates with U3 snoRNA. .

AccessionsO75691
ENST00000261637.5