UNK report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0048667Biological processcell morphogenesis involved in neuron differentiation
GO_0001764Biological processneuron migration
GO_2000766Biological processnegative regulation of cytoplasmic translation
GO_0001701Biological processin utero embryonic development
GO_0005737Cellular componentcytoplasm
GO_1990715Molecular functionmRNA CDS binding
GO_0046872Molecular functionmetal ion binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameUNK
Protein nameUnk zinc finger
RING finger protein unkempt homolog (Zinc finger CCCH domain-containing protein 5)
SynonymsZC3H5
ZC3HDC5
KIAA1753
DescriptionFUNCTION: Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development. Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system. Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif. Associated with polysomes . .

AccessionsENST00000586217.1
K7EMB1
K7EQJ1
K7EIZ1
ENST00000587501.1
ENST00000592629.1
K7ELF5
K7EQ93
ENST00000587258.1
Q9C0B0
ENST00000589666.6
ENST00000586527.1