UGDH report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015012Biological processheparan sulfate proteoglycan biosynthetic process
GO_0006065Biological processUDP-glucuronate biosynthetic process
GO_0030206Biological processchondroitin sulfate biosynthetic process
GO_0048666Biological processneuron development
GO_0034214Biological processprotein hexamerization
GO_0006024Biological processglycosaminoglycan biosynthetic process
GO_0001702Biological processgastrulation with mouth forming second
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0051287Molecular functionNAD binding
GO_0042802Molecular functionidentical protein binding
GO_0003979Molecular functionUDP-glucose 6-dehydrogenase activity

IV. Literature review

[source]
Gene nameUGDH
Protein nameUDP-glucose 6-dehydrogenase
Alternative protein UGDH
UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22)
Synonyms
DescriptionFUNCTION: Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans . Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans (By similarity). Required for proper brain and neuronal development . .

AccessionsENST00000510490.1
D6RHF4
E7ER95
E7EV97
O60701
ENST00000506179.5 [O60701-1]
ENST00000515021.5
ENST00000514106.5
ENST00000501493.6 [O60701-2]
E9PBD2
ENST00000507089.5 [O60701-3]
ENST00000505698.1
E7ER83
L8E902
ENST00000503779.5
ENST00000509391.1
E7ETF4
ENST00000316423.11 [O60701-1]
ENST00000510881.5