Insufficient scRNA-seq data for expression of UCN3 at single-cell level.
Insufficient scRNA-seq data for expression of UCN3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 99% | 108.05 | 326 / 328 | 79% | 42.57 | 140 / 178 |
| intestine | 88% | 74.80 | 849 / 966 | 42% | 3.16 | 220 / 527 |
| kidney | 75% | 23.92 | 67 / 89 | 26% | 0.63 | 237 / 901 |
| stomach | 62% | 17.80 | 223 / 359 | 29% | 13.57 | 84 / 286 |
| lung | 37% | 20.98 | 213 / 578 | 36% | 15.07 | 419 / 1155 |
| adrenal gland | 19% | 9.91 | 50 / 258 | 23% | 23.95 | 53 / 230 |
| bladder | 0% | 0 | 0 / 21 | 16% | 1.60 | 81 / 504 |
| esophagus | 4% | 0.68 | 51 / 1445 | 11% | 2.16 | 21 / 183 |
| prostate | 5% | 0.83 | 13 / 245 | 9% | 1.08 | 43 / 502 |
| brain | 10% | 4.71 | 258 / 2642 | 0% | 0 | 0 / 705 |
| uterus | 2% | 0.44 | 3 / 170 | 6% | 0.65 | 29 / 459 |
| ovary | 0% | 0 | 0 / 180 | 7% | 0.31 | 31 / 430 |
| peripheral blood | 3% | 0.58 | 28 / 929 | 0% | 0 | 0 / 0 |
| breast | 0% | 0.22 | 2 / 459 | 2% | 11.80 | 22 / 1118 |
| thymus | 2% | 0.52 | 15 / 653 | 0% | 0 | 0 / 605 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.04 | 1 / 45 |
| liver | 0% | 0 | 0 / 226 | 2% | 0.08 | 7 / 406 |
| skin | 0% | 0.03 | 5 / 1809 | 0% | 0.00 | 2 / 472 |
| adipose | 0% | 0.06 | 5 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0.05 | 1 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.02 | 2 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.02 | 1 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0009749 | Biological process | response to glucose |
| GO_0007586 | Biological process | digestion |
| GO_0035902 | Biological process | response to immobilization stress |
| GO_0032024 | Biological process | positive regulation of insulin secretion |
| GO_0042594 | Biological process | response to starvation |
| GO_0031669 | Biological process | cellular response to nutrient levels |
| GO_0045838 | Biological process | positive regulation of membrane potential |
| GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| GO_0009755 | Biological process | hormone-mediated signaling pathway |
| GO_0051412 | Biological process | response to corticosterone |
| GO_0071456 | Biological process | cellular response to hypoxia |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0043679 | Cellular component | axon terminus |
| GO_0043196 | Cellular component | varicosity |
| GO_0005179 | Molecular function | hormone activity |
| GO_0051429 | Molecular function | corticotropin-releasing hormone receptor binding |
| GO_0051431 | Molecular function | corticotropin-releasing hormone receptor 2 binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | UCN3 |
| Protein name | Urocortin-3 (Stresscopin) (Urocortin III) (Ucn III) |
| Synonyms | SPC |
| Description | FUNCTION: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. |
| Accessions | Q969E3 ENST00000380433.5 |