Insufficient scRNA-seq data for expression of UCMA at single-cell level.
Insufficient scRNA-seq data for expression of UCMA at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 80% | 13.67 | 144 / 180 | 3% | 0.21 | 11 / 430 |
| brain | 50% | 6.05 | 1331 / 2642 | 2% | 0.03 | 13 / 705 |
| uterus | 37% | 2.42 | 63 / 170 | 3% | 0.28 | 13 / 459 |
| blood vessel | 32% | 2.32 | 423 / 1335 | 0% | 0 | 0 / 0 |
| heart | 32% | 2.33 | 272 / 861 | 0% | 0 | 0 / 0 |
| liver | 19% | 0.58 | 44 / 226 | 0% | 0.02 | 2 / 406 |
| bladder | 19% | 0.62 | 4 / 21 | 0% | 0.09 | 1 / 504 |
| muscle | 18% | 0.79 | 141 / 803 | 0% | 0 | 0 / 0 |
| lung | 15% | 0.49 | 84 / 578 | 0% | 0.01 | 5 / 1155 |
| breast | 13% | 0.35 | 59 / 459 | 1% | 0.05 | 8 / 1118 |
| adipose | 11% | 0.28 | 129 / 1204 | 0% | 0 | 0 / 0 |
| prostate | 9% | 0.27 | 23 / 245 | 0% | 0 | 0 / 502 |
| peripheral blood | 9% | 0.32 | 82 / 929 | 0% | 0 | 0 / 0 |
| spleen | 9% | 0.33 | 21 / 241 | 0% | 0 | 0 / 0 |
| intestine | 8% | 0.22 | 78 / 966 | 1% | 0.01 | 3 / 527 |
| esophagus | 7% | 0.18 | 102 / 1445 | 1% | 0.01 | 1 / 183 |
| kidney | 6% | 0.15 | 5 / 89 | 1% | 0.01 | 5 / 901 |
| stomach | 4% | 0.08 | 13 / 359 | 2% | 0.04 | 6 / 286 |
| pancreas | 5% | 0.15 | 18 / 328 | 0% | 0 | 0 / 178 |
| thymus | 4% | 0.12 | 29 / 653 | 0% | 0 | 0 / 605 |
| adrenal gland | 3% | 0.10 | 9 / 258 | 0% | 0 | 0 / 230 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.07 | 1 / 29 |
| skin | 3% | 0.09 | 57 / 1809 | 0% | 0.00 | 1 / 472 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0048706 | Biological process | embryonic skeletal system development |
| GO_0060392 | Biological process | negative regulation of SMAD protein signal transduction |
| GO_0045668 | Biological process | negative regulation of osteoblast differentiation |
| GO_0001649 | Biological process | osteoblast differentiation |
| GO_0005576 | Cellular component | extracellular region |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0036122 | Molecular function | BMP binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | UCMA |
| Protein name | Unique cartilage matrix-associated protein Unique cartilage matrix-associated protein [Cleaved into: Unique cartilage matrix-associated protein C-terminal fragment (Ucma-C) (Gla-rich protein) (GRP)] |
| Synonyms | C10orf49 |
| Description | FUNCTION: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface. . FUNCTION: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface. . |
| Accessions | Q8WVF2 ENST00000463405.2 ENST00000378681.8 R4GMV7 |