I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 20% ± 5% | |
| glutamatergic neuron | 3 studies | 25% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 20% ± 5% | |
| glutamatergic neuron | 3 studies | 25% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 18% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1008.70 | 1445 / 1445 | 100% | 9.64 | 183 / 183 |
| prostate | 100% | 1114.29 | 245 / 245 | 100% | 10.95 | 502 / 502 |
| stomach | 100% | 765.75 | 359 / 359 | 100% | 9.29 | 286 / 286 |
| thymus | 100% | 852.31 | 653 / 653 | 100% | 10.46 | 605 / 605 |
| breast | 100% | 979.69 | 459 / 459 | 100% | 11.35 | 1117 / 1118 |
| brain | 100% | 793.42 | 2636 / 2642 | 100% | 10.82 | 705 / 705 |
| ovary | 100% | 916.36 | 180 / 180 | 100% | 12.17 | 429 / 430 |
| intestine | 100% | 1049.43 | 966 / 966 | 100% | 9.22 | 525 / 527 |
| adrenal gland | 100% | 843.44 | 258 / 258 | 100% | 11.06 | 229 / 230 |
| bladder | 100% | 1143.00 | 21 / 21 | 99% | 8.94 | 501 / 504 |
| skin | 100% | 1143.71 | 1809 / 1809 | 99% | 10.87 | 469 / 472 |
| kidney | 100% | 700.94 | 89 / 89 | 99% | 7.79 | 894 / 901 |
| lung | 100% | 787.95 | 576 / 578 | 99% | 8.36 | 1149 / 1155 |
| pancreas | 100% | 497.79 | 327 / 328 | 99% | 7.80 | 177 / 178 |
| uterus | 100% | 1162.49 | 170 / 170 | 99% | 8.66 | 454 / 459 |
| liver | 100% | 365.50 | 225 / 226 | 98% | 5.43 | 396 / 406 |
| adipose | 100% | 826.20 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1041.96 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 12.41 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 9.01 | 29 / 29 |
| muscle | 100% | 1288.88 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 873.52 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 7.97 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.61 | 1 / 1 |
| heart | 98% | 491.57 | 841 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 769.25 | 907 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0000209 | Biological process | protein polyubiquitination |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005925 | Cellular component | focal adhesion |
| GO_0005634 | Cellular component | nucleus |
| GO_0034450 | Molecular function | ubiquitin-ubiquitin ligase activity |
| GO_0031625 | Molecular function | ubiquitin protein ligase binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | UBOX5 |
| Protein name | U-box domain containing 5 RING finger protein 37 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RNF37) (U-box domain-containing protein 5) (UbcM4-interacting protein 5) (hUIP5) (Ubiquitin-conjugating enzyme 7-interacting protein 5) |
| Synonyms | RNF37 KIAA0860 UBCE7IP5 UIP5 |
| Description | FUNCTION: May have a ubiquitin-protein ligase activity acting as an E3 ubiquitin-protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. . |
| Accessions | A2A2Q6 ENST00000217173.7 [O94941-1] ENST00000348031.6 [O94941-2] ENST00000449731.1 O94941 |
