Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 15 studies | 22% ± 4% | |
smooth muscle cell | 11 studies | 19% ± 4% | |
pericyte | 10 studies | 21% ± 7% | |
myofibroblast cell | 6 studies | 20% ± 3% | |
connective tissue cell | 6 studies | 29% ± 9% | |
astrocyte | 6 studies | 22% ± 6% | |
endothelial cell | 5 studies | 22% ± 5% | |
glutamatergic neuron | 4 studies | 41% ± 14% | |
epithelial cell | 3 studies | 28% ± 11% | |
GABAergic neuron | 3 studies | 42% ± 2% | |
oligodendrocyte precursor cell | 3 studies | 22% ± 3% | |
basal cell | 3 studies | 20% ± 4% | |
interneuron | 3 studies | 37% ± 16% | |
oligodendrocyte | 3 studies | 20% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 3430.71 | 180 / 180 | 100% | 56.29 | 429 / 430 |
prostate | 100% | 3194.29 | 244 / 245 | 100% | 56.49 | 500 / 502 |
breast | 99% | 2215.83 | 456 / 459 | 99% | 48.78 | 1108 / 1118 |
lung | 99% | 2622.82 | 571 / 578 | 99% | 48.21 | 1147 / 1155 |
bladder | 100% | 3376.43 | 21 / 21 | 98% | 54.78 | 492 / 504 |
uterus | 100% | 5580.05 | 170 / 170 | 98% | 47.12 | 448 / 459 |
esophagus | 98% | 3852.70 | 1419 / 1445 | 99% | 62.40 | 181 / 183 |
kidney | 98% | 2039.46 | 87 / 89 | 98% | 43.12 | 880 / 901 |
thymus | 99% | 2694.68 | 649 / 653 | 96% | 53.76 | 578 / 605 |
adrenal gland | 96% | 1715.48 | 248 / 258 | 95% | 37.11 | 218 / 230 |
intestine | 97% | 3096.73 | 934 / 966 | 92% | 30.42 | 485 / 527 |
skin | 95% | 3795.83 | 1726 / 1809 | 84% | 26.65 | 396 / 472 |
brain | 78% | 984.15 | 2059 / 2642 | 99% | 43.01 | 699 / 705 |
stomach | 83% | 1981.10 | 298 / 359 | 91% | 34.88 | 261 / 286 |
pancreas | 17% | 162.36 | 57 / 328 | 98% | 42.31 | 174 / 178 |
blood vessel | 100% | 9414.40 | 1335 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 38.90 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 24.54 | 1 / 1 |
adipose | 99% | 2536.21 | 1196 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 72% | 16.52 | 21 / 29 |
heart | 71% | 950.12 | 611 / 861 | 0% | 0 | 0 / 0 |
spleen | 67% | 754.90 | 162 / 241 | 0% | 0 | 0 / 0 |
liver | 8% | 70.19 | 18 / 226 | 31% | 5.21 | 125 / 406 |
muscle | 23% | 216.24 | 182 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 19% | 1029.00 | 176 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 15% | 1.88 | 12 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030511 | Biological process | positive regulation of transforming growth factor beta receptor signaling pathway |
GO_2000515 | Biological process | negative regulation of CD4-positive, alpha-beta T cell activation |
GO_0030097 | Biological process | hemopoiesis |
GO_0030900 | Biological process | forebrain development |
GO_0030510 | Biological process | regulation of BMP signaling pathway |
GO_0002062 | Biological process | chondrocyte differentiation |
GO_0060391 | Biological process | positive regulation of SMAD protein signal transduction |
GO_0030514 | Biological process | negative regulation of BMP signaling pathway |
GO_0030509 | Biological process | BMP signaling pathway |
GO_0001707 | Biological process | mesoderm formation |
GO_0045668 | Biological process | negative regulation of osteoblast differentiation |
GO_0030513 | Biological process | positive regulation of BMP signaling pathway |
GO_0001818 | Biological process | negative regulation of cytokine production |
GO_0043010 | Biological process | camera-type eye development |
GO_0001503 | Biological process | ossification |
GO_0007435 | Biological process | salivary gland morphogenesis |
GO_2000562 | Biological process | negative regulation of CD4-positive, alpha-beta T cell proliferation |
GO_0005615 | Cellular component | extracellular space |
GO_0008201 | Molecular function | heparin binding |
GO_0050431 | Molecular function | transforming growth factor beta binding |
GO_0005515 | Molecular function | protein binding |
Gene name | TWSG1 |
Protein name | Twisted gastrulation BMP signaling modulator 1 Twisted gastrulation protein homolog 1 |
Synonyms | TSG PSEC0250 |
Description | FUNCTION: May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity). . |
Accessions | Q9GZX9 J3QS03 ENST00000581641.1 ENST00000262120.10 [Q9GZX9-1] ENST00000583147.5 [Q9GZX9-2] |