Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 19 studies | 44% ± 21% | |
oligodendrocyte precursor cell | 8 studies | 34% ± 16% | |
retina horizontal cell | 7 studies | 52% ± 25% | |
neuron | 7 studies | 72% ± 29% | |
smooth muscle cell | 5 studies | 25% ± 9% | |
GABAergic neuron | 5 studies | 46% ± 26% | |
interneuron | 5 studies | 50% ± 23% | |
kidney loop of Henle epithelial cell | 4 studies | 34% ± 14% | |
oligodendrocyte | 4 studies | 22% ± 7% | |
Mueller cell | 4 studies | 60% ± 21% | |
glutamatergic neuron | 4 studies | 44% ± 31% | |
connective tissue cell | 3 studies | 50% ± 8% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 53% ± 28% | |
abnormal cell | 3 studies | 49% ± 12% | |
retinal ganglion cell | 3 studies | 41% ± 22% | |
glial cell | 3 studies | 25% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 14888.58 | 2642 / 2642 | 100% | 640.72 | 703 / 705 |
skin | 0% | 2.74 | 4 / 1809 | 78% | 73.56 | 368 / 472 |
adrenal gland | 1% | 29.34 | 3 / 258 | 50% | 36.61 | 115 / 230 |
intestine | 29% | 430.85 | 279 / 966 | 7% | 4.02 | 38 / 527 |
kidney | 15% | 190.93 | 13 / 89 | 17% | 6.77 | 149 / 901 |
uterus | 6% | 68.76 | 10 / 170 | 21% | 33.93 | 95 / 459 |
lung | 0% | 4.40 | 2 / 578 | 21% | 18.18 | 244 / 1155 |
lymph node | 0% | 0 | 0 / 0 | 21% | 54.34 | 6 / 29 |
ovary | 1% | 9.76 | 1 / 180 | 18% | 23.25 | 78 / 430 |
esophagus | 5% | 73.81 | 71 / 1445 | 11% | 4.56 | 21 / 183 |
tonsil | 0% | 0 | 0 / 0 | 16% | 11.65 | 7 / 45 |
eye | 0% | 0 | 0 / 0 | 15% | 6.79 | 12 / 80 |
breast | 3% | 47.96 | 13 / 459 | 12% | 8.81 | 129 / 1118 |
pancreas | 0% | 7.89 | 1 / 328 | 11% | 7.98 | 20 / 178 |
stomach | 2% | 25.71 | 8 / 359 | 7% | 4.57 | 21 / 286 |
bladder | 0% | 0 | 0 / 21 | 9% | 15.86 | 47 / 504 |
peripheral blood | 9% | 202.12 | 81 / 929 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 5% | 2.35 | 20 / 406 |
prostate | 2% | 24.60 | 4 / 245 | 1% | 0.45 | 6 / 502 |
thymus | 0% | 0 | 0 / 653 | 1% | 2.18 | 8 / 605 |
blood vessel | 1% | 18.22 | 15 / 1335 | 0% | 0 | 0 / 0 |
adipose | 1% | 11.65 | 8 / 1204 | 0% | 0 | 0 / 0 |
heart | 0% | 2.00 | 1 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1902669 | Biological process | positive regulation of axon guidance |
GO_0050804 | Biological process | modulation of chemical synaptic transmission |
GO_0000278 | Biological process | mitotic cell cycle |
GO_0007017 | Biological process | microtubule-based process |
GO_0001764 | Biological process | neuron migration |
GO_0000226 | Biological process | microtubule cytoskeleton organization |
GO_0021987 | Biological process | cerebral cortex development |
GO_1990403 | Biological process | embryonic brain development |
GO_0098685 | Cellular component | Schaffer collateral - CA1 synapse |
GO_0005874 | Cellular component | microtubule |
GO_0072686 | Cellular component | mitotic spindle |
GO_0045171 | Cellular component | intercellular bridge |
GO_0015630 | Cellular component | microtubule cytoskeleton |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005200 | Molecular function | structural constituent of cytoskeleton |
GO_0005525 | Molecular function | GTP binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0046982 | Molecular function | protein heterodimerization activity |
GO_0005515 | Molecular function | protein binding |
GO_0003924 | Molecular function | GTPase activity |
Gene name | TUBB2B |
Protein name | Tubulin beta-2B chain Tubulin beta chain |
Synonyms | |
Description | FUNCTION: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers . Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. Plays a critical role in proper axon guidance in both central and peripheral axon tracts . Implicated in neuronal migration . . FUNCTION: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. . |
Accessions | Q9BVA1 A1L195 ENST00000259818.8 |