Insufficient scRNA-seq data for expression of TSSK4 at single-cell level.
Insufficient scRNA-seq data for expression of TSSK4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 99% | 98.55 | 1431 / 1445 | 98% | 4.05 | 179 / 183 |
| brain | 96% | 81.20 | 2538 / 2642 | 94% | 5.21 | 665 / 705 |
| pancreas | 98% | 68.95 | 323 / 328 | 87% | 2.33 | 154 / 178 |
| lung | 99% | 99.35 | 575 / 578 | 83% | 2.54 | 963 / 1155 |
| stomach | 97% | 84.16 | 349 / 359 | 81% | 2.18 | 233 / 286 |
| breast | 99% | 98.83 | 455 / 459 | 77% | 2.54 | 864 / 1118 |
| intestine | 100% | 125.60 | 965 / 966 | 75% | 1.90 | 397 / 527 |
| kidney | 99% | 64.67 | 88 / 89 | 74% | 2.53 | 669 / 901 |
| thymus | 100% | 119.80 | 650 / 653 | 73% | 2.00 | 442 / 605 |
| ovary | 100% | 100.48 | 180 / 180 | 73% | 1.99 | 312 / 430 |
| prostate | 100% | 89.55 | 244 / 245 | 71% | 1.69 | 357 / 502 |
| uterus | 99% | 111.78 | 169 / 170 | 64% | 1.75 | 296 / 459 |
| bladder | 95% | 98.57 | 20 / 21 | 67% | 1.72 | 336 / 504 |
| skin | 99% | 120.86 | 1797 / 1809 | 61% | 1.31 | 288 / 472 |
| adrenal gland | 98% | 94.43 | 254 / 258 | 56% | 1.23 | 129 / 230 |
| spleen | 100% | 112.21 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 99% | 81.90 | 1192 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 82.29 | 1320 / 1335 | 0% | 0 | 0 / 0 |
| heart | 87% | 40.63 | 749 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 81% | 73.55 | 750 / 929 | 0% | 0 | 0 / 0 |
| liver | 62% | 21.27 | 139 / 226 | 19% | 0.41 | 77 / 406 |
| muscle | 78% | 29.72 | 629 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 60% | 1.72 | 27 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 55% | 1.83 | 16 / 29 |
| eye | 0% | 0 | 0 / 0 | 44% | 0.86 | 35 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0032793 | Biological process | positive regulation of CREB transcription factor activity |
| GO_0009566 | Biological process | fertilization |
| GO_0035556 | Biological process | intracellular signal transduction |
| GO_0006468 | Biological process | protein phosphorylation |
| GO_0030317 | Biological process | flagellated sperm motility |
| GO_0007286 | Biological process | spermatid development |
| GO_0001669 | Cellular component | acrosomal vesicle |
| GO_0036126 | Cellular component | sperm flagellum |
| GO_0044877 | Molecular function | protein-containing complex binding |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0005524 | Molecular function | ATP binding |
| GO_0004674 | Molecular function | protein serine/threonine kinase activity |
| GO_0106310 | Molecular function | protein serine kinase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0000287 | Molecular function | magnesium ion binding |
| Gene name | TSSK4 |
| Protein name | Aurora kinase (EC 2.7.11.1) Testis-specific serine/threonine-protein kinase 4 (TSK-4) (TSSK-4) (Testis-specific kinase 4) (EC 2.7.11.1) (Serine/threonine-protein kinase 22E) AT03158-like protein (Testis-specific serine kinase 4, isoform CRA_c) Testis specific serine kinase 4 |
| Synonyms | STK22E TSSK5 hCG_40189 C14orf20 |
| Description | FUNCTION: Serine/threonine kinase which is involved in male germ cell development and in mature sperm function (By similarity). May be involved in the Cre/Creb signaling pathway (By similarity). Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells . Phosphorylates CREM on 'Ser-116' in vitro (By similarity). Phosphorylates ODF2 on 'Ser-95' (By similarity). . |
| Accessions | ENST00000643387.1 [Q6SA08-1] ENST00000645264.1 [Q6SA08-3] Q8IZN1 ENST00000287913.10 [Q6SA08-1] ENST00000645272.2 [Q6SA08-2] H0YJB1 H7C3J1 ENST00000556621.5 [Q6SA08-3] H0YJ36 ENST00000339917.10 [Q6SA08-2] ENST00000553766.1 Q6SA08 ENST00000555092.1 ENST00000428351.2 |