Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 8 studies | 29% ± 8% | |
natural killer cell | 6 studies | 21% ± 5% | |
astrocyte | 5 studies | 26% ± 8% | |
epithelial cell | 4 studies | 27% ± 8% | |
type I pneumocyte | 4 studies | 19% ± 2% | |
oligodendrocyte precursor cell | 4 studies | 25% ± 7% | |
CD8-positive, alpha-beta T cell | 4 studies | 18% ± 1% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 20% ± 3% | |
CD16-negative, CD56-bright natural killer cell, human | 3 studies | 20% ± 2% | |
GABAergic neuron | 3 studies | 39% ± 2% | |
glutamatergic neuron | 3 studies | 47% ± 2% | |
dendritic cell | 3 studies | 28% ± 2% | |
basal cell | 3 studies | 20% ± 2% | |
plasmacytoid dendritic cell | 3 studies | 23% ± 5% | |
effector CD8-positive, alpha-beta T cell | 3 studies | 17% ± 1% | |
interneuron | 3 studies | 38% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 959.83 | 180 / 180 | 100% | 13.67 | 430 / 430 |
stomach | 100% | 1010.89 | 359 / 359 | 100% | 10.53 | 286 / 286 |
uterus | 100% | 1436.07 | 170 / 170 | 100% | 13.44 | 459 / 459 |
esophagus | 100% | 1340.85 | 1444 / 1445 | 100% | 11.83 | 183 / 183 |
breast | 100% | 1206.87 | 459 / 459 | 100% | 15.19 | 1117 / 1118 |
brain | 100% | 1335.81 | 2638 / 2642 | 100% | 15.11 | 705 / 705 |
thymus | 100% | 1464.91 | 653 / 653 | 100% | 10.69 | 604 / 605 |
lung | 100% | 1401.73 | 577 / 578 | 100% | 15.06 | 1155 / 1155 |
prostate | 100% | 1252.41 | 245 / 245 | 100% | 9.04 | 501 / 502 |
intestine | 100% | 1378.34 | 965 / 966 | 100% | 10.30 | 526 / 527 |
skin | 100% | 1318.24 | 1803 / 1809 | 100% | 13.34 | 472 / 472 |
bladder | 100% | 1356.29 | 21 / 21 | 100% | 11.04 | 502 / 504 |
pancreas | 100% | 683.45 | 328 / 328 | 99% | 9.00 | 177 / 178 |
liver | 100% | 584.47 | 226 / 226 | 99% | 6.71 | 403 / 406 |
adrenal gland | 100% | 1338.10 | 258 / 258 | 99% | 7.82 | 228 / 230 |
kidney | 100% | 906.81 | 89 / 89 | 97% | 5.54 | 876 / 901 |
adipose | 100% | 1223.87 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 10.94 | 29 / 29 |
spleen | 100% | 1105.83 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 10.71 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.42 | 1 / 1 |
muscle | 100% | 1224.23 | 802 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1300.41 | 1332 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 1053.54 | 849 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 83% | 4.13 | 66 / 80 |
peripheral blood | 72% | 711.42 | 672 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006397 | Biological process | mRNA processing |
GO_0006388 | Biological process | tRNA splicing, via endonucleolytic cleavage and ligation |
GO_0005730 | Cellular component | nucleolus |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005515 | Molecular function | protein binding |
GO_0003676 | Molecular function | nucleic acid binding |
Gene name | TSEN15 |
Protein name | Chromosome 1 open reading frame 19, isoform CRA_a (tRNA splicing endonuclease subunit 15) tRNA-splicing endonuclease subunit Sen15 (SEN15 homolog) (HsSEN15) (tRNA-intron endonuclease Sen15) tRNA splicing endonuclease subunit 15 |
Synonyms | SEN15 hCG_40901 C1orf19 |
Description | FUNCTION: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini . There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events . . |
Accessions | ENST00000533373.6 ENST00000647437.1 A0A2R8YHG0 A0A2R8Y5L0 ENST00000645668.2 [Q8WW01-1] ENST00000643916.1 ENST00000644145.1 A0A2R8YEM0 A0A2R8YDU8 ENST00000646297.2 ENST00000643231.1 ENST00000423085.7 [Q8WW01-2] H0YCV5 ENST00000644815.1 Q8WW01 ENST00000644592.1 ENST00000645963.2 E9PPN1 ENST00000485209.6 A0A2R8YG40 A0A2R8Y6B3 ENST00000643702.1 F2Z3M0 A0A2R8Y6M5 ENST00000644479.1 A0A2R8Y5W5 ENST00000361641.6 A0A2U3TZM3 A0A2R8Y5Q6 A0A2R8Y6A4 ENST00000647465.1 ENST00000462677.3 |