TRPV2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TRPV2 at tissue level.

III. Associated gene sets

GO_0098703Biological processcalcium ion import across plasma membrane
GO_0007600Biological processsensory perception
GO_0120162Biological processpositive regulation of cold-induced thermogenesis
GO_0045773Biological processpositive regulation of axon extension
GO_0009266Biological processresponse to temperature stimulus
GO_0070588Biological processcalcium ion transmembrane transport
GO_0090280Biological processpositive regulation of calcium ion import
GO_0044297Cellular componentcell body
GO_0042470Cellular componentmelanosome
GO_0032584Cellular componentgrowth cone membrane
GO_0009986Cellular componentcell surface
GO_0005886Cellular componentplasma membrane
GO_0044295Cellular componentaxonal growth cone
GO_0005216Molecular functionmonoatomic ion channel activity
GO_0015075Molecular functionmonoatomic ion transmembrane transporter activity
GO_0005515Molecular functionprotein binding
GO_0005262Molecular functioncalcium channel activity
GO_0005261Molecular functionmonoatomic cation channel activity

IV. Literature review

[source]
Gene nameTRPV2
Protein nameTransient receptor potential cation channel subfamily V member 2 (TrpV2) (Osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1)
Transient receptor potential cation channel subfamily V member 2
SynonymsVRL
DescriptionFUNCTION: Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. .

AccessionsK7EIQ6
ENST00000577277.6
H7BZK2
K7EKG5
ENST00000580788.6
Q9Y5S1
ENST00000338560.12
K7EPY7
ENST00000581560.5
ENST00000455666.1
K7ELL3
ENST00000577865.2