TRNAU1AP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001514Biological processselenocysteine incorporation
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0000049Molecular functiontRNA binding
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameTRNAU1AP
Protein nametRNA selenocysteine 1-associated protein 1 (SECp43) (tRNA selenocysteine-associated protein 1)
SynonymsSECP43
TRSPAP1
DescriptionFUNCTION: Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis (By similarity). .

AccessionsENST00000373830.4 [Q9NX07-1]
Q9NX07