TRMT6 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TRMT6 at tissue level.

III. Associated gene sets

GO_0006397Biological processmRNA processing
GO_0030488Biological processtRNA methylation
GO_0031515Cellular componenttRNA (m1A) methyltransferase complex
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameTRMT6
Protein nametRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (mRNA methyladenosine-N(1)-methyltransferase non-catalytic subunit TRM6) (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6)
SynonymsKIAA1153
TRM6
CGI-09
DescriptionFUNCTION: Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA . Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries . .

AccessionsQ9UJA5
ENST00000203001.7 [Q9UJA5-1]
ENST00000453074.6 [Q9UJA5-4]